XII.

DRUG STUDY

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NAME OF DRUG Generic: Biperiden hydrochloride Brand: Akineton Classificatio n: Anticholinergi c, Antiparkinsoni an drug

DOSAGE, FREQUENCY, TIMING AND ROUTE DOSAGE: 2mg FREQUENCY: BID TIMING: 8am, 6pm ROUTE: Per orem

MECHANISM OF ACTION Unknown.

INDICATION

CONTRAINDICATIO N Hypersensitivity biperiden

ADVERSE REACTION

NURSING RESPONSIBILITIES C: Anticholinergic, Antiparkinsonian drug H: decreased or diminished EPS and Parkinson symptoms E: best taken after meals (after breakfast and lunch) to avoid gastric irritation C: do not use with antidiarrheals 1-2 hours after taking drug : avoid activities that may require mental alertness : change position slowly to avoid sudden drop in BP K: Monitor clients output; increase intake of fluids, fruit juices and fiber to avoid 47 constipation

As an adjunct in the therapy of Blocks central all forms of cholinergic parkinsonism receptors, (idiopathic, helping to postencephaliti balance c, cholinergic arteriosclerotic) activity in the basal ganglia. Control of extrapyramidal disorders secondary to neuroleptic drug therapy

to Fatigue, dizziness, drowsiness, dry Narrow angle mouth, rarely glaucoma swelling of salivary glands, Bowel obstruction accommodation difficulties, Megacolon mydriasis and photophobia, hypohydrosis, constipation, nausea, tachycardia, dyskinesia, ataxia, muscle twitching, speech impairment

DOSAGE, FREQUENCY, TIMING AND ROUTE Generic: DOSAGE: Diphenhydrami 50 mg per capsule ne hydrochloride FREQUENCY: HS Brand: Benadryl TIMING: HS Classification : ROUTE: Anticholinergic Per orem , Antiparkinson drug

NAME OF DRUG

MECHANISM OF ACTION Competes with histamine for H1 receptor site. Prevents, but doesnt reverse, histamine mediated responses particularly those of bronchial tubes, GI tract, uterus and blood vessels.

INDICATION Parkinsonism

CONTRAINDICATIO N

ADVERSE REACTION
CNSdrowsiness, confusion, insomnia, headache, vertigo, sedation, sleepiness, nervousness, restlessness CVpalpitations, hypotension, tachycardia EENT blurred vision, nasal congestion, tinnitus GIT nausea and vomiting, dry mouth, constipation, anorexia GUT dysurea, urine retention, urinary frequency Hema hemolytic anemia, thrombocytopenia, agranulocytosis Respi thickening of bronchial secretions Skin Urticaria, photosensitivity, rash, Other anaphylactic shock

NURSING RESPONSIBILITIES
C: Anticholinergic, Antiparkinsonian H: (-) allergy, decreased or diminished EPS symptoms, (+) sedation E: Best taken with food if GI upset occurs C: Avoid alcohol : Report difficulty of breathing K : Administer syrup form if patient is unable to take tablets : Assess for allergy : Warn patient not to take this drug with any other products that contain diphenhydramine (including topical therapy) because of increased adverse reactions.

Used to anxiety, tension, sleeplessness or involuntary movements due to the side effects of certain psychiatric drugs.

Contraindicated in patients with treat hypersensitivity to drug. Avoid use in patients taking MAO inhibitors Caution in patients with asthma, COPD.

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NAME OF DRUG Generic: Flupentixol Brand: Fluanxol Classificatio n: antipsychotic

DOSAGE, FREQUENCY, TIMING AND ROUTE Dosage: cc Frequency: 2 weeks for 1 month Route: IM

MECHANISM OF ACTION Works by affecting the activity of a natural compound called dopamine in the brain. *flupentixol usually starts to produce an antidepressant effect within two to three days.

INDICATION

CONTRAINDICATIO N

ADVERSE REACTION

NURSING RESPONSIBILITIES C: antipsychotic H: treat depression and anxiety (+) drowsiness, and blurred vision E: Best meal taken after

Severe depression Depression, requiring with or electroconvulsive without therapy (ECT) or anxiety.

Abnormal movements of the hands, legs, face, neck and tongue, hospitalization. e.g. tremor, twitching, rigidity States of excitement or (extrapyramidal overactivity, including effects). mania. Anxiety, People with a restlessness and decreased level of agitation consciousness due to (akathisia). any cause (e.g., intoxication with Increased alcohol, barbiturates or salivation or dry opiates). mouth. Rare hereditary problems of fructose intolerance, glucosegalactose malabsorption or sucrase-isomaltase insufficiency (Fluanxol tablets contain sucrose). Sleepiness.

C: Avoid drinking alcohol while taking this drug

Rhythmical involuntary movement tongue, mouth and jaw, which may sometimes be accompanied by involuntary movements of the arms and legs

K: Do not drive or operate machinery : Be aware that although that this medicine may start to work in 2-3 days it may not make you feel fully of the better for at least 2 face, weeks.

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