www.ghbn.
or g
Bio-Matrix
On Brains
and Bugs
If microbial
research, outbreaks
of epidemics, and
brain research are
your interests or
disciplines, then plan
to attend the second
annual Health Research
in the City conference on
Wednesday, February 6.
The one-day event –
titled Brains and Bugs
Conference – at Hamilton
Convention Centre
features keynote panel
presentations, network
discussions, and poster
awards.The day will
highlight research
programs and promote
interaction on clinical,
knowledge transfer, health
services and other levels.
Go to www.ghbn.org and
click on Events for more
information or to register.
Inside –
n Biofuels special
report
[pages 2, 3]
n Tiny sentinals
of safety
[page 4]
n Million-dollar
mouse
[page 6]
pilot trial. n
Golden Horseshoe
Biosciences Network
n W inter 2008 n volume 2 n issue 1
New clinical trial program set to go
A unique clinical trials program for medical devices is underway in Hamilton – a project that may
result in a permanent base in the city.
The pilot program, involving a handful of companies with assistive devices ready to test, will rely
on medical and related expertise within McMaster University and Hamilton Health Sciences.
If the pilot flies as well as its backers hope, the plan is that it will lead to a full program, with
government and other funding.
The idea is that a fully funded program would come to be known as the home of clinical
testing for Class 1 technologies – many of whose backers now go to the U.S. or offshore
to get their external devices vetted for market. The backers also hope to lure Class 1
manufacturers, such as makers of prostheses, wireless devices and hearing-loss systems,
to locate in Hamilton area.
At present, entrepreneurial companies that have medical and assistive device technologies
have no real established program in Ontario to access for clinical oversight.
“We recognize small and medium enterprises have difficulties getting clinical testing of
products that have reached the commercialization (stage),” said Mickey Milner, of the
Health Technology Exchange. HTX is a provincially funded centre that aids both research
and to-market aspects of medical and assistive devices.
“There isn’t any formal program for them. Basically, people are on their own to make these
connections and linkages,” said Milner, president and CEO of Markham-based HTX, which is
providing the lion’s share of the $200,000 budget.
The pilot project involves four major partners: HTX, the Golden Horseshoe Biosciences
Network (also a funder), McMaster University, and Hamilton Health Sciences. It would
utilize the medical and related expertise, facilities, ethical review boards and other existing
infrastructure in Hamilton.
The city is internationally known as a prime venue for conducting clinical trials. For example,
the Population Health Research Institute, at the university and HHS, has for years done
trials and provided expertise in cardiovascular, diabetes, epidemiological and other areas. Morris (Mickey)
Milner
A permanent trials base for medical devices would be a further example of employing
President and CEO,
such expertise. The Health Technology
Exchange (HTX)
“There is an opportunity here that hasn’t really been tapped yet,” said Darlene Homonko,
executive director of the Golden Horseshoe network. “We want to attract companies to come
here . . . It’s all the various supports we can offer that helps build the opportunities.”
Medical device makers approved for the clinical trials pilot will benefit from having their products
tested on users, will have access to specialist clinician and other help, and may be able to take
advantage of other assistance, such as business advice or contacts, or be connected to related
technology companies.
The successful Ontario applicants must provide at least half the operational costs for their particular
 www.ghbn.or g
Nilesh Patel, left,
and Corey Centen
with the CPR glove
Grabbing new
honours
The CPR Glove has
grabbed more honours
as one of the year’s most
inventive discoveries in
science and technology.
The custom-made glove,
designed to assist
in cardio-pulmonary
resuscitation efforts,
won in the undergraduate
category at the Collegiate
Inventors’ Competition in
California.
Three McMaster
University inventors
– Corey Centen, Nilesh
Patel and Sarah Smith
– received a $15,000
prize in the competition,
an annual program of the
National Inventors Hall
of Fame Foundation in
the U.S.
The glove, outfitted
with sensors and an
LCD screen, was
also recognized by
TIME magazine in
its Inventions of
the Year special
edition.

In search of tomorrow: the path to ‘green’ energy
In a fifth-floor lab at McMaster University, biophysicist
Duane Chung studies one of the world’s most simple yet
abundant aquatic plants in search of tomorrow’s fuels.
If he and fellow researchers at the
University of Waterloo succeed, they
will help turn algae lipids into a
renewable fuel. Through genetic
engineering and better photo
bioreactor reactor design to
drive algae growth, they hope
to harvest alternative energy
from the chlorophyll-bearing
organism.
“To be realistic, I would say it’s going
to take a while before we’re beginning to make this
happen,” says Chung, the head of Centurion Biofuels.
It’s a fair statement, easily applied to much of the
research going on around the world as scientist-
entrepreneurs seek ‘green’ solutions to the problems of
rising oil and gas prices, the need for a secure energy
supply, and toxic greenhouse gases (GHGs).
Burlington resident Norm Rathie and his company,
Met-Tech Inc. are working with a U.S.-based partner
on “a 100 per cent chemical approach” that can use
grass clippings or corn stover (the stalks left behind after
harvest) or other biomass while husbanding its carbon
content.
They hope to produce ethyl levulinate, which can be
an additive to diesel fuel; levulinic acid, a precursor
for many chemical manufacturing processes; furfural,
an industrial chemical; and formic acid, among other
products.
With biomass, says Rathie, it’s all about “yield, yield,
yield”, as researchers seek green fuels that can compete
cost-effectively with petro-fuels.
There are great expectations from biofuels.
But there are great obstacles too. And the
high cost of feedstock – and the
research and development costs that go into converting
it – is only one of the barriers as proponents strive to
create an economically viable industry.
“It’s still a tough area and clearly, part of the issue
you’ve got is there are other alternatives out
there that are more cost-effective,” says John
Neate, of the non-profit OCETA (Ontario
Centre for Environmental Technology
Advancement). Too many people look for
“the silver bullet,” he says.
OCETA ran a one-day biofuels workshop at
McMaster in late October. (Go to: http://www.
oceta.on.ca/workshops/hamilton/biofuels.htm)
The seminar zeroed in on some barriers. They included:
n The need to integrate a renewable-fuels structure
within existing petro-fuel production and supply
systems as much as possible
n A system for environmental gains to be ‘monetized’,
such as through tradeable GHG emissions-reduction
credits
n The necessity for diversified product revenue
streams to help offset the ‘sunk costs’ of harvesting,
preparation, and transport of bio-feedstocks.
The young biofuel industry is years from being a viable
sector. And ironically, just like petro-fuel facilities, green
fuel production has lately taken flak for environmental
and economic fallout, whether it’s about smell or land
spoilage.
The food-corn-to-ethanol strategy has reaped a bumper
crop of criticism. Critics have slammed subsidies and use
of nitrogen fertilizers. The Organization for Economic Co-
operation and Development suggests the global biofuel
rush pushes up food prices.
The debate has been so intense that the Canadian
Renewable Fuels Association complained
in November to the United Nations
about a harsh UN special report.
 www.ghbn.or g

Biofuels: ‘some really good work’ on choices

Association president Gordon Quaiattini wrote that Governments are using both push and prod to move the
biofuels provide “one of the most sensible and attractive country toward renewable fuels. Ottawa, for example,
solutions to date, particularly considering (their) has set up a $500 million NextGen Biofuels Fund
contribution to the reduction of CO2 emissions.” to jumpstart production of large-scale, first-of-kind
demo-scale plants. The 2007 federal budget included a New OCETA
In the U.S., says Jay Mullin of OCETA, the industry has
run into “stranded ethanol” problems as supply outruns
renewable-fuels producer payment offering $1.5 billion
over seven years to domestic ethanol and biodiesel
head
infrastructure. Ethanol, notes Met-Tech’s Norm Rathie, producers. Kevin Jones, formerly
is almost a way-station, an intermediate step to more
chief operating officer
efficient bioenergy. Biobutanol, points out OCETA’s Mona In Ontario, the government is providing more than $500
El Hallak, is more similar to gasoline than is ethanol, with million over 12 years to aid increased ethanol production. of OCETA, has been
a higher energy density. In Alberta, a new federal-provincial initiative will help named president and
develop micro-algae systems that would capture CO2 chief executive officer
Yet the successes are undeniable. Gasoline and diesel from industrial sources. of the non-profit centre.
prices that hover at $1 or more a litre help fuel the push
He replaces Ed Mallett,
to cleaner-burning biofuel. So, researchers are looking Ottawa is also mandating that gasoline consist of 5 per
at microbes, biomass conversion, syngas from garbage, cent renewable content by 2010. Diesel fuel and heating who has held the post
biodiesel made from used restaurant grease, and other oil must be 2 per cent green by 2012. since OCETA’s inception in
feedstock options. 1994. Mallett retains ties
Biomass is the great green hope in Canada. Sustainable with the centre as senior
Oakville-based Biox Corp., with its initial production plant Development Technology Canada (SDTC) believes
associate focused on new
in Hamilton, processes raw materials, including animal there is enough grass and forest feedstock to satisfy
fats, recycled cooking oils, and palm oil. The company about 6 per cent of the country’s energy needs through business development.
hopes to go public with an upcoming IPO offering. production of non-digestible cellolosic ethanol.
Jones joined OCETA in
Energy giants, such as Suncor, are helping to evolve the One biofuels industry estimate puts the energy value 1997 as vice-president
chemical valley of Sarnia-Lambton into a bio-industrial at 2.2 exajoules a year – or 17 per cent of Canada’s marketing and business
corridor. The new Guelph pyrolysis plant of B.C.-based total energy – within the next decade or so if there is development and has been
Dynamotive Energy Systems is turning wood waste into increased use of waste biomass and crop dedication
instrumental in extending
BioOil. to biofuels. (That 2.2 exajoules works out to an energy
equivalent of about 62 billion litres of gasoline.) its reach into such
OCETA is among the groups helping to bring investors, areas as industrial eco-
distribution-system players, end-users, and biofuel “We have a decent critical mass of young Canadian efficiency and brownfield
producers together. It’s “a tough go” for small- to companies that have done some really good work in this remediation.
medium-sized enterprises to secure needed capital, says area,” Vicky Sharpe, president and chief executive officer
Neate. But if they have a of SDTC, administrator of the NextGen fund, said last fall. OCETA, the Ontario
better idea, it makes sense “I don’t think people have grasped what the bioenergy Centre for Environmental
to join a similar-interests industry could look like.” n
Technology Advancement,
consortium.
is a non-profit agency
providing value-added
business services in aid
of commercialization
and application
of innovative
environmental
and energy
technologies.


 www.ghbn.or g
Tomas Hudlicky
Pain relief has
its pleasure
Making pain relief
medication safer and
greener has earned
Brock University
professor Tomas Hudlicky
a $30,000 cheque from
healthcare-products
maker Noramco Inc. in the
university’s first licensing
deal with a pharmaceutical
company.
Hudlicky, Canada Research
Chair and Professor
in the Department of
Chemistry and Centre for
Biotechnology, received
the license fee for his
team’s work in developing
new analgesic compounds
and the processes for
producing them.
Manufacture of
analgesics and various
antagonists used in
addiction treatment
has relied on a
potentially toxic class
of substances. The
work of Hudlicky and
his team focuses
on developing
shorter and more
environmentally
benign methods
of synthesis by
combining chemical
and biological
methods.

Tiny sentinels of safety
Biotech sensors that can detect and kill deadly unseen dangers are among the latest initiatives for McMaster
University researchers. And an audience at Metro Hall in Toronto heard last fall how this nanotechnology early-
warning system could be set up on sheets of paper.
Dr. Robert Pelton (left), a professor of chemical engineering, told the audience that the
researchers behind the Sentinel Bioactive Paper Network hope to identify and repel waterborne
and airborne pathogens. The idea is to develop bioactive paper products, such as a face mask,
that could be impregnated with nanosensors.
The idea is to develop bioactive paper products, such as a
face mask, that could be impregnated with nanosensors.
These impossibly small – a nanometre is a billionth of a metre – sensors might protect against the SARS virus
or trap pathogens in water purification equipment or be used as security papers to support anti-counterfeiting,
brand protection, and document authentication.
A sensor-laden mask might inform the wearer of viral contamination via a change in colour or odour, Pelton
told The Biotechnology Initiative (TBI) audience on October 18. Such a mask might also deactivate the
pathogen. Another use of Sentinel technology might be the design of diagnostic paper with applications in the
food, health and biodefence sectors.
The Sentinel strategy is to target “low-hanging fruit” (e.g. biorecognition
agents such as antibodies, enzymes, bacteriophage and DNA aptamers)
and to determine how to make these agents work on paper.
The challenges include designing these sensors with enough stability
to survive on paper in dehydrated form and in the diverse conditions
of daily life, and with adequate recognition and sensitivity-reporting
properties. Intrigued by the initiative, the New York Times magazine
included Sentinel technology in the “Year in Ideas” issue published in
early December.
Pelton is Canada Research Chair in Interfacial Technologies and Sentinel’s scientific director. The network
encompasses 11 Canadian universities, eight founding industrial partners, and three government agencies.
Created in 2005, the network brings leading-edge research to the attention of key players in the Canadian pulp
and paper industry. The network has a five-year budget of about $10 million, funded primarily by NSERC.
Pelton was joined in his TBI address by Dr. John Preston, director of the Brockhouse Institute for Materials
Research and leader of the McMaster Initiative in Nano Innovation (profiled in the fall 2007 Bio-Matrix issue).
He talked about nanostructured materials – in the 1 to 100 nanometre range – and outlined how nanoscale
substances differ from macroscale matter.
Materials at the nano level exhibit “exotic” robust properties that aid in designing new systems and devices
within many industrial sectors, said Preston. The entire nanotechnology field takes in several research and
academic disciplines and has “tight interplay” with biotechnology. n
This article was prepared from research contributed by Nora Cutcliffe, PhD, BioPharma Consultant.
 www.ghbn.or g

Ontario’s networks of growth

Ontario’s innovation networks – including the Golden The RINs bring together universities, hospitals and research
Horseshoe Biosciences Network – have got it right, says a centres, government commercialization units, business
U.S. national science and technology organization. supports and other elements needed to push economic
growth.
The 12 regional innovation networks (RINs) are “a potential Brownfielder
model for other states and provinces to consider” in
improving and revitalizing economic innovation, says the
Originally targeted at the life sciences clusters of research
and industry, the RIN program has been expanded to
of the year
Ohio-based State Science and Technology Institute. include innovation strengths of each region. For example, The Canadian Urban
the Guelph Partnership for Innovation has centred on
Institute has named
The RINs help to bust through walled-in industry and developing a one-stop location for agribusiness, agri-
communication silos and bust out beyond cities to region- food, and life sciences. Mark Brickell,
centred economies, the non-profit institute noted in a vice-president of smart
December newsletter. “The RINs have become expert-driven portals to growth and partnerships
commercialization programs and services,” said the for Niagara Economic
Too often, said the SSTI, local economic departments and Ontario report, released in November. The report
Development Corp.,
government offices have led to competing jurisdictions. offered several examples of area inter-regional
These infrastructure silos tended to compete against each collaboration. as its Brownfielder
other and were not well suited to introducing scientific gains of the Year.
and technology innovations to help grow area economies. n The Golden Horseshoe Biosciences Network, it
noted, has partnered with BioDiscovery Toronto, the Brickell was recognized
They stumbled in taking advantage of the ‘cluster’ strengths Western Greater Toronto Area Convergence Centre, for spearheading private
– such as health care or agriculture – in each area and in and YORKbiotech on an annual speaker series – all sector brownfield projects
reaching out to collaborate with each other. of them are working with the Institute of Electrical
in the region, which
Engineers.
The RIN structure has helped area economies and the n GHBN, said the report, has joined with the City of has offered financial
province to develop “an integrated province-wide Hamilton and McMaster University to develop a incentives, in co-ordination
commercialization support system”, said the SSTI. business plan for the bioscience incubation centre with other public bodies,
The Ohio institute was commenting on a new report issued that will go into McMaster Innovation Park. that have leveraged
by the Ontario government, which set up the RINs three n GHBN has also worked with BioDiscovery Toronto
millions of dollars in non-
years ago. These networks, argues the Ontario report – see and YORKbiotech (among others) on a U.S.-
http://www.utoronto.ca/onris/research_review/Related/ Canada partnering event on medical-devices government investment.
DOCS/RIN2007_ReportMRI.pdf – help move the technology technologies. n
transfer of ideas and technologies to market faster. In recent years,
brownfield cleanups in
North America have
Growing Opportunities included innovative
bioremediation, such
Vineland seeks two research chair candidates as using naturally
occurring microbes in
Vineland Research and Innovation Centre continues its research renaissance as it seeks candidates to fill two soils and groundwater
research chairs at the complex in Niagara Region. to expedite treatment
The centre, a government and industry-led initiative, is looking for a new chair for its greenhouse and ornamentals and in-situ oxidation,
research position as well as a scientist for its chair in tender fruit/sensory research. a strategy that uses
oxygen or oxidant
The positions are part of a wider vision developed by Vineland, a 220-acre site in Lincoln, as it builds new laboratories chemicals to
and takes on new research initiatives in horticulture, ornamentals, and greenhouse growth. The research involves both
enhance a cleanup.
innovation in and commercialization of new high-value species and improving the sustainability of Niagara fruit.

This latest round of hiring follows last summer’s appointment of research scientist and university professor Jim Brandle
as CEO of the internationally renowned non-profit centre. The Ontario and federal governments also announced
$28 million in investment over the next few years for the agri-food and plant centre. n

 www.ghbn.or g
Firsts in
innovation
McMaster University
health-related entries
took top spots at the
inaugural TECNet Smart
Start Innovation Fair
held at the University of
Waterloo.
Winovi, a wireless
technology platform run by
students Alena Morozova
and Aizhan Tursunbayeva,
delivers peer-reviewed
summarized medical
studies and knowledge to
health-care professionals
on their wireless devices.
Another entry, using
RFID technology to
track and manage
hospital inventory, was
also honoured. Both
enterprises, out of
McMaster’s Xerox
Centre for Engineering
Entrepreneurship
and Innovation, were
among several
business pitches
made to investors
and venture
capitalists at the
October innovation
years in later life.
fair.
“If we can take that and extend our ability to be functioning and contributing members of our society . . .
to me that is far more important than being able to live for a long time.” n

A quest for the million-dollar mouse
It has been an age-old mythical quest: longer life, a suspension of aging,
with death on hold.
For Jennifer Lemon and her colleagues, the pursuit of a fuller,
extended life has led to an international competition, with a
$1 million prize, involving the classic lab mouse.
The Hamilton scientist is among scores of researchers in the
Methuselah Foundation’s Mprize challenge. Their goal is to
keep the mouse, Mus musculus, alive for at least four years.
That’s double the average life span in captivity.
If investigators can dodge disease in a mouse and keep it mentally
and physically fit, argues the U.S.-based Methuselah foundation, this success can be a critical precursor
in developing human anti-aging techniques.
“Other than the very pragmatic basis of this competition, it provides opportunities for like-minded
scientists to develop collaborations and push each other intellectually in pursuit of our common goal,”
said Lemon.
Well qualified to raise Methuselah mouse and to improve the odds in life’s lottery, she has seen the
degradation in cell membrane function, mitochondrial breakdown, and impaired glucose metabolism in
lab mice. Her doctorate involved a focus on the biology of free radicals, highly reactive molecules that
can promote aging and lead to cellular damage, including the death of brain cells.
Scientists have long known that antioxidants – examples are vitamins C and E and beta-carotene – can
help combat free radical damage, a kind of “rusting from the inside out,” says Lemon. So it makes sense
that a nutrient package high in antioxidants might help neutralize free radicals in the body.
Working with other McMaster scientists, including Ph.D. supervisors and mentors David Rollo and Doug
Boreham, she developed a diet elixir of 31 items, many of them antioxidants. Supplement-fed mice lived
up to 15 per cent longer, equivalent perhaps to a decade longer in humans.
The supplement not only stalled disease, it also helped keep the mice smarter as they motored through
a maze.
Now, the supplement has interested oncologists as they try to counter the toxic impacts of chemo and
radiation therapy on healthy cells. Cancer specialists wonder about its benefits for their patients, says
Lemon, the 2006 winner of the Exceptional Student Award from the International Society of Analytical
Cytology.
But there is a very personal reason for Lemon’s research. Thirteen years ago, she lost her paternal
grandmother, Jean Lemon, who died at age 85. In Jean’s last years, she underwent “a fairly severe
cognitive decline.” Warm memories of her provide a clear motivation in Lemon’s search for more quality

An industry aging nicely
The Canadian wine industry has aged well since free trade
with the U.S. changed the rules in 1989. A sector then
labelled as mediocre was thrust into a new game with
tougher and larger competitors.
Almost two decades later, the industry is still around. Armed
with novel research, innovation in breeding new strains, and
a hardy independent streak, it has survived and prospered.
“Pound for pound, for the size of this industry, which is a
small industry internationally, Canada punches above its
weight,” says Paul-André Bosc, vice-president of marketing
and administration at Chateau des Charmes, in the Niagara
Peninsula.
He’s right. According to Agri-Food Canada, Canada has only
about 10,000 hectares of vineyards. California’s Napa Valley,
alone, has more than 16,000. But the Canadian industry has
been vitalized in the post-free trade era. Niagara vineyards
that went for $10,000 an acre at free trade now sell for four
to six times that amount, said Bosc Jr. Industry tax revenue
comes in at about $200 million today versus perhaps
$2 million pre-free trade, he adds.
Yet Canadian wineries don’t even have a lock on retail sales
in their own country. Within Canada, interprovincial barriers,
such as the Importation of Intoxicating Liquors Act, still
restrict east-west wine flows. And freer trade means shelves
bulge with products from the U.S., Europe, Australia and
other winemaking nations.
It’s also hard for Canadians to crack outside markets but
very profitable when it happens. Chateau des Charmes,
for example, sells its icewine to U.S. retailers, Bosc Jr. told
visitors to the chateau recently.
“Fewer than 20 Costco (stores) in Southern California have
bought more icewine from us than the Liquor Control Board
of Ontario.”
The miniscule size of Canada’s industry means winemakers
must be very deliberate in where they plant, how
www.ghbn.or g
they spend, and what they research. And they have Dare to
to collaborate. That’s what the tour to the chateau and
to the Cool Climate Oenology and Viticulture Institute, at
dream a little
Brock University, heard in October.
If you’re a
Ontario’s new grape and wine research foundation biosciences student
illustrates the collaboration theme, with funds to be
with an entrepreneurial
raised from levies on grapes tonnage and wine literage.
The levy will amount to $3.50 a tonne from each of flair – perhaps you have
Ontario’s wineries and growers, said Bosc Jr. Money for an idea for a medical
research and development will also come from other device to assist patients
sources, such as the Niagara Community Foundation.
– then the Xerox Centre
The research is broad and involves the wineries, biotech for Entrepreneurship
companies, government centres and universities, and Innovation has a
including CCOVI at Brock and the University of Guelph. contest for you.
R & D studies include the impact of Niagara’s micro-
climate on wine quality, how to deal with the Asian
lady beetle infestation (associated with an earthy taint The McMaster Nicol
in wines), and how to help vines survive Canadian Entrepreneurship
winters (which includes use of temperature-raising Challenge is a business
wind turbines).
pitch competition for
Chateau des Charmes research has included students to realize their
development of about 600 new varietals. If only five entrepreneurial dreams
or six make the market, says Paul Bosc Sr., “it’s going – and take a crack at up
to have a significant impact on our company.” His to $6,000 in prizes.
enterprise, founded in 1978, is one of several now
striving for sustainable environment certification. To
gain that standing, wineries must focus on their water Deadline for registering
management, energy conservation, recycling of organics is February 5. Go to
and other environmentally responsible practices.
www.mcmasternicol
The industry is even researching authentication of challenge.com
its majestic icewines. At CCOVI, said director Isabelle for competition details
Lesschaeve, they are looking at the chemical marker and to register.
signposts of quality icewine. That’s because some foreign
packagers use bulk-frozen grapes to make icewines
instead of harvesting ripe fruit from the
vines on cool pre-winter nights. n

 www.ghbn.or g
VC activity
still healthy
Venture capital
investment in life
sciences and biopharma
companies continued
at a healthy clip in the
third quarter of 2007.
Just over $150 million
was disbursed to 30
companies in this sector,
says Canada’s Venture
Capital and Private Equity
Association.
That total was more than
double the $61 million of
one year ago. Investment
in life sciences amounted
to about 29 per cent
of VC activity in all
sectors, with information
technology the big winner.
Year to date, total VC
activity in all sectors
stands at $1.6 billion.
Much of the growth
“is being driven by an
increasing focus on
Canadian transactions
by U.S. venture
firms,” noted CVCA
president Rick
Nathan.
Contact

Innovation CafeTM Series Innovation Night – Bringing Ideas to Life
Date: February 6, 2008
Medical Diagnostics – The Future is Nano...
Time: 7:00 p.m. 
Date: January 30, 2008 Location: Slainte Irish Pub, 33 Bowen St.
Time: 4:30 - 6:30 p.m.  City: Hamilton
Location: Golden Horseshoe Biosciences Network For more information: To register as a presenter
City: Hamilton
For more information: www.ghbn.org
or for further information contact Elaine Holding,
SB Partners at eholding@sbpartners.ca or Cindy
Porter, Trivaris at cindy.porter@trivaris.com
Events
Science in the City –
Business to Business Partnering
Opportunities with South Eastern US The Promise and Perils
Medical Device Mission of Nanotechnology
Date: January 30-31, 2008 Date: February 12, 2008
Location: MaRS, 101 College Street Time: 7:00 p.m. 
City: Toronto Location: The Hamilton Spectator
For more information: (416) 973-5190, Auditorium, 44 Frid Street
City: Hamilton
or email: trnto@international.gc.ca
For more information: Visit:
Breaking Through Barriers – www.mcmaster.ca/research/ScienceintheCity.htm
Advancing Ontario Biomed Technology
(Ontario Centres of Excellence (OCE) CEO Entrepreneurship Bootcamp:
Mind to Market Breakfast Series) “Managing the Growth of your Company”
Date: February 14, 2008
Date: January 31, 2008
Time: 7:30 a.m - 9:00 a.m. Time: 8:30 a.m - 4:30 p.m.
Location: MaRS, 101 College Street, CR-3
Location: Toronto Board of Trade
City: Toronto City: Toronto
For more information: http://m2m.oce-ontario.org/ For more information: contact Marcelle Canido
at 905-248-2728 or admin@htx.ca or visit
Health Research in the City – Brain and Bugs http://www.ledc.com/newsevents/events/
savethedate/std.html
Date: February 6, 2008
Time: 8:00 a.m. - 3:30 p.m. 
Medical Device Approvals Process –
Location: Hamilton Convention Centre
Strategies to Meet FDA Regulatory
City: Hamilton
Compliance
For more information: www.ghbn.org
Date: March 3-4, 2008
City: Toronto
For more information: contact International
Pharmaceutical Academy (IPA) at 416-410-7402
or visit www.ipacanada.com 
Golden Horseshoe Biosciences Network
McMaster University, Michael G. DeGroote Centre for Learning & Discovery
5105-1200 Main Street West, Hamilton, Ontario, CANADA L8N 3Z5
n Ana Paredes Office Administrator/Incubator Assistant – Tel: 905-525-9140 Ext. 26602 Fax: 905-528-3999
n Darlene Homonko Executive Director – Tel: 905-525-9140 Ext. 26609 Web: www.ghbn.org
GHBN News is a quarterly newsletter published by GHBN. Director and editor: Darlene Homonko
Writer: Mike Pettapiece Contributor: Nora Cutcliffe Graphic Design: Nadia DiTraglia