Develop a bone-integration method to permanently implant limb prosthesis

By Lokesh Patil

Introduction
1.7 million people with limb loss in US Types of available lower limb prosthesis Limitations of socket type prosthesis - Skin irritations -Bone deterioration -Soft tissue damage -Need for refitting

Contd..

Osseointegration
What is Osseointegration Different stages of osseointegration Factors affecting osseointegration

Titanium properties

Current bone-integration methods

Two stages of surgeries performed Stage 1- Implant is fixed in medullary cavity Stage 2: Abutment fixed after 6 months

Advantages of bone-anchored prosthesis

Lower feeling of weight More and precise control over prosthesis No pain, perspiration and soft tissue damage No need for socket replacement Easy donning and doffing Osseoperception

Disadvantages
Two surgeries needed at gap of around six months Relatively long Rehabilitation time High risk of deep-infection Chances of loosening of implant from the bone

Proposed design
Using a grid blasted ribbon type implant Incorporation of porous coating of tantalum Rough surface rather than smooth Proper fail-safe mechanism

Limitations, future work and ethics

Limitations -Not enough clinical data -High costs of the method Future Work - Use of antimicrobial membranes - Incorporation of soft tissues for load transfer

Ethics
Debated use in sports Can be afforded by a small section of society

Questions