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Classifications of Thyroid Tumours
Classifications of Thyroid Tumours
Classifications of Thyroid Tumours
THYROID TUMORS
BENIGN
MALIGNANT
PRIMARY
SECONDARY
DIFFERNTIATED
UNDIFFERENTIATED
PARAFOLLICULAR
LYMPHOID
FOLLICULAR
ANAPLASTIC
MEDULLARY
LYMPHOMA
PAPILLARY
THYROID TUMORS
BENIGN
FOLLICULAR ADENOMA PRIMARY DIFFERENTIATED - FOLLICULAR - PAPILLARY UNDIFFERENTIATED - ANAPLASTIC PARAFOLLICULAR - MEDULLARY LYMPHOID CELL - LYMPHOMA SECONDARY METASTASIS
MALIGNANT
FOLLICULAR ADENOMA - Presents as a solitary nodule - Seen approx in 1% population - It is characterised by 4 features - Solitary nodule - Complete encapsulation - Clearly distinct architecture - Compression of the thyroid parenchyma
PAPILLARY CARCINOMA - It is a most common type of thyroid carcinoma - Comprises of 70-80% - Slow growing malignant tumor - It presents as a asymptomatic solidary nodule - Involvement of regional lymph nodes common.
PAPILLARY CARCINOMA
FOLLICULAR CARCINOMA - It comprises of 10-12% - Common in females - It can occur denovo or in a pre-existing multi nodular goitre. - It presents either as a solitary nodule or irregular firm & nodular thyroid enlargement. - Blood borne metastasis is more common.
FOLLICULAR CARCINOMA
MEDULLARY CARCINOMA - It is less frequent (5%) - It arises from the parafollicular cells - There are 3 distinctive features - Familial occurance - Secretion of calcitonin - Amyloid stroma - Regional lymph node metastasis may occur.
MEDULLARY CARCINOMA
ANAPLASTIC CARCINOMA - It comprises of <5% of all thyroid tumors - This occurs commonlyn in 7th & 8th decades - The tumor is wildely aggressive & rapidly growing - Local infiltration is early feature of this tumor.
MALIGNANT LYMPHOMA - It is NHL type. - Occurs in pre-existing Hashimotos Thyroiditis. - Chemotherapy is the main treatment.
PAPILLARY
FOLLICULAR ANAPLASTIC
MEDULLARY
AETIOLOGY
Irradiation
Unknown
Sporadic or familiar 6%
INCIDENCE
60%
13%
AGE
20-40yrs
30-50yrs
>50yrs
Middle age
DIAGNOSIS
MICROSCOPY
SPREAD
INVESTIGATIO FNAC N
Frozen section
TREATMENT OF PRIMARY
TREATMENT OF METASTASIS
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