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Mitral Stenosis: Mustafizul Aziz Assistant Professor Nicvd
Mitral Stenosis: Mustafizul Aziz Assistant Professor Nicvd
Mitral Stenosis: Mustafizul Aziz Assistant Professor Nicvd
INTRODUCTION
Mitral stenosis, an obstruction to blood flow between LA and LV is caused by abnormal mitral valve function. 60% patients with MS donot give H/O rheumatic fever. 50& of patients with acute carditis do not eventually have valvular heart diseases.
AV alone 3%
CAUSE
Rheumatic carditis (in virtually all patients) Congenital MS(rareLutembachers syndrome Massive mitral valve annular calcification.
PATHOLOGY
Mitral Stenosis
Shortened diastole (Tachycardia) Loss of AV Synchrony (AFib, heart block) Pulmonary Venous Flow (Volume loading)
LVEDP
Atrial Arrhythmias
Pulmonary Edema Pulmonary Arterial Hypertension RVH and RV Hypertension TR and RVE
Symptoms
CLINICAL FEATURE
Symptoms
SIGN
Mitral facies. Orthopnic. Pulse-normal/ low volume/tachycardia/AF. BP-Normal JVP-Normal/raised-prominent a wave in sinus rhythm/prominent v wave inTR /absent a wave in AF
Precordium
Tapping Apex beat Diastolic thrill at the apex A parasternal lift. Palpable P2. S1loud S2 may be loud. MDM, opening snap,presystolic accentuation. Pansystolic murmur graham Steel murmur
SEVERITY OF MS
CLINICAL Full length diastolic murmur. Short A2-os interval. A2 os may be longer in severe MS if there is associated moderate to severe AR Pulmonary hypertension.
SEVERITY OF MS
ECHOCARDIOGRAM MVA plenimitry(normal 4-6 cm2) Mild -1.5-2.5cm2 moderate 1.00-1.5cm2 severe <1.00cm2
Transmitral pressure gradient (Doppler study) Normal up to 10 mmHg Mild -10- 15mmHg Moderate-15-20mmHg Severe->20mmHg
WILKINS SCORE
GRADE
Mobility
Highly mobile valve,only leaflet tip restricted
Leaflet mid &base portions have normal mobility
Subvalvular thickening
Minimal thickening just below MV leaflet Chordal structure up to 1/3rd of length
Thickening Calcification
2
3
Move forward Up to distal mainly from 1/3rd base No/minimal forward movement Extensive thickening& shortening-
SOME QUESTIONS
Why S1 is loud Short note on OS Why OS Causes of MDM Presystolic accentuation. Chest pain in MS Indication of CAG in MS
INVESTIGATION
NATURAL HISTORY
10 survival of patient with MS without symptom is 84% MS with mild symptom 10 year survival is 34%to42% MS with moderate to severe symptom 20 year survival is <10%
TREATMENT
MEDICAL TREATMENT
Antibiotic prophylaxis(rheumatic &IE) Restrict activities. Arrhythmia Prevent or control Atrial fibrillation-control ventricular rate, anticoagulation, restore sinus rhythm Treatment of heart failure Treatment of other complication (LA thrombus,systemic emboli).
Treatment of LA thrombus OMC &removal of thrombus Otherwise anticoacoagulation by I/V heparin with aim of endotheliolized
WARFARIN USED IN
AF Systemic emboli LA thrombus Pulmonary emboli LV systolic dysfunction.
INTERVENTIONAL-PTMC/CBC
Sellers Grading of MS
Sellers grade I: Cmmisural fusion, leaflet thickening No sub-valvular involvement, No calcification. Echo display diastolic dooming.
Sellers Grading of MS
Sellars Grade-II
Commisural fusion, leaflet thickening Mild to moderate sub-valvular involvement, minimal calcification. Echo- Funneling of mitral orifice Treatment: OMC
Sellers Grading of MS
Sellers grade III:
Commisural fusion, leaflet thickening Significant sub-valvular involvement, Significant calcification. Echo Disorganized valve.
CONTRAINDICATION TO PTMC
Related to valve MR that is truly 3+4+ Thrombus in LA Unfavorable valve morphology,commissural Ca MS mild. Related to centre
Need for open heart surgery Procedural difficulties Severe TR Huge RA Distorted /displaced IAS Venous problem.
OMC
CLASS-I
Balloon valvotomy is not available All indication to PTMC but there is LA thrombus despite anticoagulation Patients in NYHA III-IV, moderate to severe MS & anon pliable or calcified valve with the decision to proceed either repair or replacement made at the time of operation.
MVR
Patients who are not candidate for PTMC or repair
MS IN PREGNANCY
The increased CO tachycardia, fluid retention may double PG across the MV Symptom become apparent 20th week,may aggravated further. Maternal death is rare when there careful attention to the management of CCF.