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Somatropin
Somatropin
Sarah Al-Gethami
Pharm II
Growth hormone is a peptide hormone secreted by the pituitary gland that stimulates growth and cell reproduction. It is produced by recombinant DNA technology and is prescribed for a variety of reasons.
Functions:
Stimulate linear and skeletal growth. Increases number and size of skeletal muscle cells. Increases RBC mass and internal organ size. Increases cellular protein synthesis.
Uses:
In Children:
Treatment
of growth failure.
Treatment
of short stature.
Uses:
In Adults:
A growth hormone deficiency . HIV+ adults with cachexia . Adults with short bowel syndrome.
Dosage:
For adults:
Hormone Replacement Therapy : 0.004 mg/kg/day - 0.016 mg/kg/day AIDS Wasting or Cachexia:
More 45 35
less
Dosage
In
pediatrics:
Administration:
It
Nordilet
It
Step
1:
the solution .
Pull off the cap .
Check the solution .
Check
Step 2 :
Dispose
Step
3:
Hold the pen with needle with the needle stillthe pointing pointing push upwards . upwards the button on the bottom .. Tap the cartridge with your finger a A drop of the solution should appear few times to make sure that the .bubbles collect at the top. If a drop doesnt appear after 6 air shots DO NOT use the pen ..
Step
4:
the dose :
Dial
Put
Make
Step 4 :
the dial in the direction shown to set the dose you want.
scale on the pen cap shows the number of clicks.
Every
The
time you make a full turn , 5 clicks will me set on the push button.
scale will show (5, 10, 15, 20 or 25 ) clicks .
Example :
Turn the pen cap one full turn so that 0 is next to the dosage indicator again .. you have now selected 5 clicks and 5 will appear on the push button scale .. Now continue turning the pen cap scale until 3 is next to the dosage indicator . Add the 3 from the cap scale and 5 from the dose scale and you have selected 8 clicks ..
Add the number on the pen cap to the highest number shown on the push button scale .. If you have set a wrong dose, simply turn the pen cap forwards or backwards until the right number of clicks is set .. The maximum dose you can set is 29 clicks . If you try to set the dose at higher than 29 clicks, growth hormone will leak out of the needle and the dose will be wrong .
Step 5 :
the area that you inject so that you dont harm your skin . the needle into your skin vertically .. the dose by pressing the push button all the way in .. the injection keep the needle under the skin for at least 6 seconds and then withdraw it . the push button fully depressed until you remove it from the skin.
Insert
Deliver After
Keep
Step
6:
the needle:
the outer needle cap .. And remove the
Remove
Replace
needle .
Always
If
Quick tool
1st step:
2nd step:
3rd step:
4th step:
Contraindications:
Hypersensitivity to growth hormone. Growth promotion in pediatric patients with closed epiphyses.
Adverse Reactions:
In Children:
Arthralgia. Edema Injection
site reaction.
Headache Hypothyroidism.
Muscle
Psoriasis
exacerbation.
Adverse Reactions:
In Adults:
Arthralgia. Myalgia. Peripheral
Edema.
Flu-like
edema.
syndrome.
Paresthesia. Skeletal
Headache.
pain.