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net
Transvaginal Sonography and Endometrium
Galal Lotfi. MD, MRCOG
Professor Obstetrics & Gynecology
Suez Canal University
Egypt
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Aim Of Work
To stydy the efficacy of TVS in
dignosing abnormal
Endometrial pattern in
postmenopausal women
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Introduction
Screening Methods Include:
Pap Smear; specificity and
sensitivity
Endometrial cytology
Office Biopsy; Clinical and
technical difficulties
D&C add anestetic hazards and
limitations
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Drawbacks
Smear: lack of specificity and sensitivity
Endometrial cytology: Clinical and
technical difficulties
Office Biopsy; Clinical and technical
difficulties
D&C: Invasive, Costly, Anesthesial
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Design
Antrospective study for
Postmenopausal women,
without or with
postmenopausal bleeding
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Material and Methods
Postmenopausal women
with no bleeding , n=187
Postmenopausal women
with bleeding, n=132.
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Material and Methods, cont..
All women were subjected to
TVS for pelvic assessment and
endometrial thickness measurement
Pap smea
D&C biopsy

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Mareial and Methods cont
Postmenopausal women without bleeding
n=187
group Ia: high risk group n=36
group Iib: low risk group n=131

Postmenopausal woen without bleeding n=187
group Ia: high risk group n=72
group Iib: low risk group n=60

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Risk Factors:
Diabetes
Hypertension
Obesity
Previous abnormal smea
PCO
Family History
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RESULTS
Table (1): TVS results of group I; postmenopausal women without bleeding. (n=187)
Endometrial thickness High Risk Group LowRisk Group X2 P
Endometrial thickness
=<4mm
31 117 25.3 <0.005
Endometrial thickness
>4<8mm
7 8 1.4 NS
Endometrial thickness
>8<12mm
12 5 12.7 <0.005
Endometrial thickness >12 6 1 8.3 <0.005
Total 56 131
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Results

Table (1): TVS results of group I; postmenopausal women without bleeding. (n=187)
Endometrial thickness High Risk Group Low Risk Group X2 P
Endometrial thickness
=<4mm
31 117 25.3 <0.005
Endometrial thickness
>4<8mm
7 8 1.4 NS
Endometrial thickness
>8<12mm
12 5 12.7 <0.005
Endometrial thickness >12 6 1 8.3 <0.005
Total 56 131
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Results cont.
Table (2): TVS results of group II; postmenopausal women with bleeding. (n=132)
Endometrial thickness High Risk Group Low Risk Group X2 P
Endometrial thickness
=<4mm
28 37 6.8 <0.005
Endometrial thickness
>4<8mm
11 10 0.05 0.8
Endometrial thickness
>8<12mm
20 9 11.1 <0.005
Endometrial thickness >12 13 4 3.7 0.05
Total 72 60
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Results cont...
Table (3): TVS results of endometrial thickness, cytology and endometrial sampling in low
risk women in groupI; postmenopausal women without bleeding. (n=131)
Endometrial thickness Abnormal sample Abnormal smear
Endometrial thickness =<4mm 0/117 0/117
Endometrial thickness >4<8mm 0/8 1/8
Endometrial thickness >8<12mm 2/5 2/5
Endometrial thickness >12 1/1 1/1
Total 3/131 3/131
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Results cont..
Table (5): TVS results of endometrial thickness, cytology and endometrial sampling in low
risk women in groupII; postmenopausal women with bleeding. (n=60)
Endometrial thickness Abnormal sample Abnormal smear
Endometrial thickness =<4mm 0/37 6/37
Endometrial thickness >4<8mm 3/10 4/10
Endometrial thickness >8<12mm 4/9 4/9
Endometrial thickness >12 3/4 4/4
Total 10/60 18/60
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Results cont..
Table (6): TVS results of endometrial thickness, cytology and endometrial sampling in low
risk women in groupII; postmenopausal women with bleeding. (n=72)
Endometrial thickness Abnormal sample Abnormal smear
Endometrial thickness =<4mm 6/28 5/28
Endometrial thickness >4<8mm 7/11 4/11
Endometrial thickness >8<12mm 13/20 17/20
Endometrial thickness >12 9/13 7/13
Total 35/72 33/72
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Results Cont..
Table (4): TVS results of endometrial thickness, cytology and endometrial sampling in high
risk women in groupI; postmenopausal women without bleeding. (n=56)
Endometrial thickness Abnormal sample Abnormal smear
Endometrial thickness =<4mm 0/31 0/31
Endometrial thickness >4<8mm 0/7 1/7
Endometrial thickness >8<12mm 2/12 5/12
Endometrial thickness >12 6/6 6/6
Total 8/56 12/56
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RESULTS
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TVS:
Delineate the endometrium
Measures the endometrila thickness
Detects associated endometrial
pathology
Detects other pathology in the pelvis
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Other pathology detected
Endometrila polyps
Samall fibroid
Adenomyosis
Hydrosaplix with PID
Ovarian cysts.

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