Professional Documents
Culture Documents
Rotigotine
Rotigotine
Rotigotine
Prepared by
Mohammad Shouli
System)
Company: UCB
Diagnosing RLS
There are four key points doctors use to diagnose RLS. They can be
described using the word URGE.
Urge to move the legssometimes accompanied by uncomfortable
sensations
Rest inducedthe urge to move gets worse during inactivity such as
resting, sitting, or lying down.
Gets better with activitymovement such as walking or stretching brings
relief, but unpleasant sensations reappear when you stop.
Evening and nightthe urge to move increases in the evening or at night or
occurs only in the evening or at night.
Mechanism of Action
Neupro is a transdermal system that provides
Pharmacokinetics
Metabolism of rotigotine occurs extensively by
Side Effects
Adverse events associated with the use of
redness
nausea
somnolence
headache
Refernces
http://www.neupro.com/
http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001810/
http://www.centerwatch.com/drug-information/fda-approval
s/drug-details.aspx?DrugID=1198