Chem.

133 1/26
Lecture

Introduction
- Instructor: Roy Dixon
Educational Background in Analytical
Chemistry and Environmental Chemistry
Most of my research currently is in HPLC
technology/methodology development
or applications

Class: Chemical
Instrumentation
General Goals of Education (copied roughly
from Dean a few years ago):

Jobs
Career
Skills
Knowledge
Member of Society
Future Life-long Learner

Main focus will be on skills and knowledge, but

sometimes it is worth looking at larger picture

Learning Objectives of Class

(Skills and Knowledge Set)
Learn how instruments work
Learn measures of instrument performance
and what affects performance
Know common applications of instruments
(e.g. how can we use an instrument to
determine a compounds concentration,
identity or structure)
Connect instrument performance with
method/sample/analyte demands

Roll Call and Adding

Students
Class normally has 12 students
Currently 10 in class and 6 on waitlist
I will add 2 from waitlist and possibly 1 or
2 more
I plan to add students in gap between
lecture and lab
Students wanting to add, but not currently
on the waitlist will need to fill in my
waitlist

Adding Students

Priority for Adding Students

1. BS Chem majors graduating S16
2. BS Chem majors graduating F16 and BA
Forensic majors graduating S16
3. Any Chem/Biochem majors graduating by F16
4. All others

Within each category, preference given to

those higher on waitlist
You may be asked to show evidence for
your graduation date

Handouts
Syllabus
Laboratory Schedule
1st Homework Assignment

Syllabus
Top 3 Items
Lab Class room = Sequoia 516, but will
spend time in other instrument rooms too
Office hours
can arrange meetings at other times

Internet Site
will post handouts, keys to homework and
exams, practice exams, Powerpoint lecture
notes, and updates (e.g. if changes to
syllabus)

Syllabus
Text Books
Harris (Quantitative Chemical Analysis)
Main text
We are using the 8th Edition, older editions could be
used but you must find the differences

Rubinson and Rubinson (Contemporary

Instrumental Analysis)
Supplementary text book
Available at library reserves
Used for electronics and NMR instruction

Skoog et al. (Principles of Instrumental Analysis)

Recommended for anyone interested in working as an
analytical chemist

Grading
Lecture Component
Exams (44% of grade)
3 midterms (see syllabus for dates)
Comprehensive Final Exam (may be ACS
multiple choice exam)

Quizzes (8% of grade)

Roughly every 2 weeks unless near exam

Homework (3% of grade)

Only a subset of problems will be turned in
(Bold problems in first set)

Grading
Lab Component
Lab Reports/Lab Practical (35% of grade)
5 lab reports (one for each lab experiment)
Each report (or lab practical) worth 7% of total grade
Possibility to replace one (and only one) lab report with a
lab practical for selected experiments
Penalties for late labs (but 1 lab 1 period late is
acceptable in exchange for attending 1 Chem 294
seminar)
More on experiments in lab outline (will discuss in lab)

Grading
Lab Component cont.
Term Project (10% of grade)
Hand out to be given out soon
Projects: J. Chem. Ed. projects (e.g. analysis of caffeine),
instrument construction (digitized bomb calorimeter),
STORC applied projects (analysis of composter methane
concentration)
Will work on in lab during last 4 to 5 weeks, but basic
due dates given earlier (e.g. topic, proposal, progress
report)
A poster presentation is required

Topics
Electronics

Emphasis on understanding multiple aspects of

electronics for instruments
Some topics will be covered qualitatively

Electrochemistry (fundamentals + qualitative

understanding of ion selective electrodes)
Spectroscopy

Fundamental sections (theory and spectrometer

components)
Specific types (UV-Visible, fluorescence, atomic, and NMR)

Mass Spectrometry
Chromatography

Theory of separations, and main components

GC and HPLC

Homework Set 1
Three subsets (1.1, 1.2, and 1.3)
Bold Homework problems are
graded; do not turn in other
problems
Subsets should be done before
quizzes
Solutions will be posted.

Todays Lecture
Measures of Instrument Performance
Overview of Electronics
Electronic Definitions and Basic Laws
covering in lab (only need blackboard)

In Lab Today
Data/Excel Basics
covering here

Checking In
First 15 pages of Lab Manual will be
on website (read before Thurs. class)

Measures of Instrument or
Method Performance
What is he talking about?
Example: method accuracy
Get class to come up with 7+ measures

Electronics
Topics Covering
Basic DC Circuits (Ohms Law, Power Law,
Kirchhoffs Laws + applications)
Alternating Currents, Other Waveforms, and
Fourier Transformation (lecture only)
RC Circuits
Diodes (lecture only)
Signal Digitization (lecture only)
Transducers (lecture only)
Noise

Electronics - Overview
Generic Instrument Block Diagram
Analog Electronics
Exciter

Digital
Electronics

sample
Digital to
Analog
(control)

Digital Signal
Processing

Transducer

Analog
Signal
Processing

Analog to Digital
Conversion Board

Memory

Long-term
Storage
(Disk)
Signal
Display

Electronics
Example Block Diagram for an Atomic Emission Spectrometer

From: David Zellmer, CSU Fresno

http://zimmer.csufresno.edu/~davidz/Chem106/ModZoo/ModZoo.html

Electronics
Go to Board to Cover: Definitions, Ohms
Law, Power Law and Kirchhoffs Laws