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ACUTE MYOCARD INFARTION

DEFINITION

RISK FACTORS
o
o
o
o
o
o
o

Modifiable
Smoking
Hypertension
Obesity
Diabetes Mellitus
Dyslipidemia
Low HDL < 40
Elevated LDL / TG

Non Modifiable
o Gender and age:
- male after age 45 y.o
- female after age 55 y.o
o Family History in first
degree
relative > 55 y.o for
male/ 65 y.o for female

PATHOPHYSIOLO
GY

American Heart Association: http://watchlearnlive.heart.org

American Heart Association: http://watchlearnlive.heart.org

American Heart Association: http://watchlearnlive.heart.org

American Heart Association: http://watchlearnlive.heart.org

ELECTROCARDIOGRAPHY

BIOMARKERS
Biochemical marker for
detection of myocardial necrosis
First rise
after
AMI

Peak
after
AMI

Return
to
normal

CK-MB

4h

24 h

72 h

Myoglobi
n

2h

6-8 h

24 h

Troponin
T

4h

24 - 48
h

5 21
d

Troponin
I

3-4 h

24 36
h

5 14
d

PRINCIPLE OF
TREATMENT

MANAGEMENT

Oxford Handbook of Clinical Medicine 6th Edition

COMPLICATION

Oxford Handbook of Clinical Medicine 6th Edition

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