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  • (V) 9. Growth Disorders & Neoplasma

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    RizkaGayo
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    Cellular growth is controlled through a balance of proliferation, differentiation, and cell death, which is determined by the cell cycle. Genetic factors like proto-oncogenes, tumor suppressor genes, apoptosis, and DNA repair regulate the cell cycle and cellular growth. Abnormal growth can occur through atrophy of cell size, hypertrophy of increased cell size, hyperplasia of increased cell number, metaplasia of one cell type changing to another, and dysplasia of abnormal cell differentiation that can potentially lead to cancer.

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    onkologi

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    (v) 9. Growth Disorders & Neoplasma

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    Cellular growth is controlled through a balance of proliferation, differentiation, and cell death, which is determined by the cell cycle. Genetic factors like proto-oncogenes, tumor suppressor genes, apoptosis, and DNA repair regulate the cell cycle and cellular growth. Abnormal growth can occur through atrophy of cell size, hypertrophy of increased cell size, hyperplasia of increased cell number, metaplasia of one cell type changing to another, and dysplasia of abnormal cell differentiation that can potentially lead to cancer.

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    7 views13 pages

    (V) 9. Growth Disorders & Neoplasma

    Uploaded by

    RizkaGayo
    Cellular growth is controlled through a balance of proliferation, differentiation, and cell death, which is determined by the cell cycle. Genetic factors like proto-oncogenes, tumor suppressor genes, apoptosis, and DNA repair regulate the cell cycle and cellular growth. Abnormal growth can occur through atrophy of cell size, hypertrophy of increased cell size, hyperplasia of increased cell number, metaplasia of one cell type changing to another, and dysplasia of abnormal cell differentiation that can potentially lead to cancer.

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    of 13

    dr. Syahruddin Saragih Sp.

    PA

    Cellular Growth Control


    Balance proliferation cell differentiationcell
    death
    Proliferation determined trough cell cycle
    Cellular growth control by genetic :

    proto-oncogen,
    supressor gen,
    apoptosis and
    DNA repair in cell cycle

    Abnormal Growth
    Atrophy : size of the cells decreased
    Disuse atrophy immobilitation
    Denervation atrophy : poliomyelitis
    Loss of Trophic hormon : Breast, endometrium
    atrophy
    Lack of nutrition : Kwashiorkhor
    Senile atrophy : Brain atrophy
    Pressor atrophy

    Abnormal Growth
    Hypertrophy : size of the cells increased
    Physiologic hypertrophy

    Hyperplasia : number of cells increased


    Endometrial hyperplasia
    Thyroid hyperplasia (Graves disease)
    Prostat hyperplasia

    Metaplasia :
    Squamous metaplasia
    Glandular metaplasia

    : cervix, bronchus
    : esophagus

    Abnormal Growth
    Dysplasia : Abnormal differentiation and maturation

    Cervix dysplasia
    Bronchial dysplasia
    Esophagus dysplasia
    Gastric dysplasia

    dysplasia is potential to be a Cancer Precancer !!!

    mauliate
    thank you
    danke
    terima kasih

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