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Antiasthmatics Anti-Inflammatory Immunosuppressives Drug: Mayramarie Lopez Flor #Rmtsoon
Antiasthmatics Anti-Inflammatory Immunosuppressives Drug: Mayramarie Lopez Flor #Rmtsoon
ANTI-INFLAMMATORY
IMMUNOSUPPRESSIVES
DRUG
Mayramarie Lopez Flor
#RMTsoon
Antiasthmatics
Drug use for Chronic obstructive pulmonary
disease or asthma
Commonly allergic in nature
Albuterol
Theophylline &
Albuterol
Drug
Half-life
Therapeautic
Toxic level
Facts
Theophylline
NS: 8-9hrs
SA: 5-6hrs
C: 3-4h
Ave:8.7 hrs(non
smokers)
5.5 h(smokers)
10-20 ug/ml
>20ug/ml
Inhibits
phosphodiestera
se to maintain
high cAMP
causing
bronchodilation
Therapeutic
index is low
Metabolites
1. 1,3
dimethyluric
acid
2. 3methylxanthi
ne
Antihistamine
Anti-inflammatory drugs
1.Acetaminophen (Tylenol)
2.Acetylsalicylic acid (Aspirin)
3.Naproxem (Naprosyn)
4.Ibuprofen (Motrin)
Drug
Half-life
Therapeutic
range
Toxic level
1. Acetaminophen
2hours
5-20mg/ml
>20mg/ml
2. Acetyl-salicylic
acid
3-15 hrs
Immunosuppressives
Cyclosporin - Therapeutic range : 250-800ng/ml in whole
blood; 50-300ng/ml in plasma
Others:
Prednisone
Cyclophosphamide
Tacrolimus
Sirolimus TR: w/ cyclosporine 4-12ug/L ; discontinued
cyclospoeine 12-20ug/L
Mycophenolic Acid
-end-
GODBLESSS!!
Heart-Heart!