Personalized drugs

Presented by
Ankit Bikram Poudel
Masters in Pharmacy
(Industrial group)

Kathmandu university

Introduction
Personalized medicine is a young but rapidly
advancing field of healthcare that is informed by each
person's unique clinical, genetic, genomic, and
environmental information. Because these factors are
different for every person, the nature of diseases
including their onset, their course, and how they might
respond to drugs or other interventionsis as
individual as the people who have them.
Personalized medicine is about making the treatment
as individualized as the disease. It involves identifying
genetic, genomic, and clinical information that allows
accurate predictions to be made about a person's
susceptibility of developing disease, the course of
disease, and its response to treatment.

 Our current apporach lack of ability to predict an individual

patients treatment success for most diseases and conditions
means that clinicians have no choice but to follow a less than
optimal approach to prescribing drugs and other treatment options.
A patient being treated for high blood pressure, for example, might
be placed on one of a number of blood pressure medications. The
patients doctor makes a decision about what medication to
prescribe based on only general information about what might
actually work for that particular patient. If the medication does not
work after a few weeks, the patient might be switched to another
medication. This somewhat trial-and-error approach can lead to
patient dissatisfaction, adverse drug responses and drug
interactions and poor adherence to treatment regimens.
The goal of personalized medicine is to streamline clinical decision
making by distinguishing in advance those patients most likely to
benefit from a given treatment from those who will incur cost and
suffer side effects without gaining benefit.

 Thus personalized mnedicine is the

ability to offer
The right drug
To the right patient
For the right disease
At the right time
With the right dosage

Advantage
Ability to make more informed medical
decisions
Higher probability of desired outcomes
thanks to better-targeted therapies
Reduced probability of negative side effects
Focus on prevention and prediction of
disease rather than reaction to it
Earlier disease intervention than has been
possible in the past
Reduced healthcare costs