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    Kuliah Dr. Dr. Sahala Panggabean, SPPD-KGH

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    Intan Kartikasari
    This document discusses glomerulonephritis (GN), including its definition and pathogenic classifications. GN is defined as an inflammatory or non-inflammatory disease of the glomerulus that causes changes in permeability, structure, and function. GN can be primary, originating from the kidneys without systemic signs, or secondary, caused by a systemic disease. Common primary GNs include minimal change disease, focal segmental glomerulosclerosis, and membranous glomerulonephritis. Prognosis depends on histopathology, with minimal change disease having the best prognosis and membranoproliferative GN having the worst.

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    Kuliah Dr. Dr. Sahala Panggabean, SPPD-KGH

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    92 views33 pages
    This document discusses glomerulonephritis (GN), including its definition and pathogenic classifications. GN is defined as an inflammatory or non-inflammatory disease of the glomerulus that causes changes in permeability, structure, and function. GN can be primary, originating from the kidneys without systemic signs, or secondary, caused by a systemic disease. Common primary GNs include minimal change disease, focal segmental glomerulosclerosis, and membranous glomerulonephritis. Prognosis depends on histopathology, with minimal change disease having the best prognosis and membranoproliferative GN having the worst.

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    Kuliah Dr. Dr. Sahala Panggabean, SpPD-KGH

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    This document discusses glomerulonephritis (GN), including its definition and pathogenic classifications. GN is defined as an inflammatory or non-inflammatory disease of the glomerulus that causes changes in permeability, structure, and function. GN can be primary, originating from the kidneys without systemic signs, or secondary, caused by a systemic disease. Common primary GNs include minimal change disease, focal segmental glomerulosclerosis, and membranous glomerulonephritis. Prognosis depends on histopathology, with minimal change disease having the best prognosis and membranoproliferative GN having the worst.

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    92 views33 pages

    Kuliah Dr. Dr. Sahala Panggabean, SPPD-KGH

    Uploaded by

    Intan Kartikasari
    This document discusses glomerulonephritis (GN), including its definition and pathogenic classifications. GN is defined as an inflammatory or non-inflammatory disease of the glomerulus that causes changes in permeability, structure, and function. GN can be primary, originating from the kidneys without systemic signs, or secondary, caused by a systemic disease. Common primary GNs include minimal change disease, focal segmental glomerulosclerosis, and membranous glomerulonephritis. Prognosis depends on histopathology, with minimal change disease having the best prognosis and membranoproliferative GN having the worst.

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    of 33

    GLOMERULONEFRITIS

    Sahala Panggabean

    Department of Internal Medicine


    Christian University of Indonesia
    Dec 15, 2016
    Structure of Glomerulus
    DEFINISI dan KLASIFIKASI PATOGENETIK

    DEFINISI GLOMERULONEFRITIS : PENYAKIT INFLAMASI ATAU


    NON INFLAMASI
    PADA GLOMERULUS YANG
    MENYEBABKAN
    PERUBAHAN
    PERMEABILITAS, PERUBAHAN
    STRUKTUR DAN FUNGSI
    GLOMERULUS.

    KLASIFIKASI GLOMERULONEFRITIS
    GN PRIMER : APABILA PENYAKIT DASAR BERASAL
    DARI GINJAL
    SENDIRI TANPA ADA TANDA
    TANDA PENYAKIT
    SISTEMIK.
    MCD = Minimal Change Disease, FSGS = Focal Segmental GlomeruloSclerosis, MGN =
    Membranous GlomeruloNephritis
    Muehrcke's nails, Muehrcke's lines, or leukonychia striata
    Xanthelasma is a sharply demarcated yellowish deposit of fat underneath the skin, usually on or around the eyelids
    HMG-CoA reductase = Hydroxy Methyl Glutaryl-Coenzyme A reductase (Statin)
    IgAN = IgA nephropathy; APSGN = Acute poststreptococcal GN; MPGN =
    Membranoproliferative GN
    Prognosis
    Prognosis of GN based on
    histopatology
    - Minimal change disease with good
    prognosis
    - MGN with moderate prognosis
    - MPGN with severe prognosis
    References
    Harrisons Principle of Internal
    Medicine, 2015
    Current Medical Diagnosis and
    Treatment, 2015
    Buku ajar Penyakit Dalam edisi ke 6,
    2014

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