SINH L GAN

Ths. Bs. Nguyn Hng H

Ging vin B mn Sinh l Khoa Y Trng i hc Y Dc
Cn Th
Liver of a sheep: (1) right lobe, (2) left lobe, (3)
caudate lobe, (4) quadrate lobe, (5) hepatic
artery and portal vein, (6) hepatic lymph nodes,
 CU TRC GII PHU

- C QUAN LN NHT, M = 1,5 KG (2%)

- TIU THU GAN: + N V CHC NNG

+ 50.000 100.000
L: vi mm
+ HNH TR
d: 0,8 1mm
 CHC NNG CA H THNG
TUN HON GAN

1050 ML: TM CA
27% CUNG
(1 PHT) LNG TIM
300 ml: M GAN

V MU TRONG MCH MU GAN: 650 ML(10%)

 CHC NNG M

BIU M MAO MCH TNH THM CAO

KIU XOANG:

H/THU NHANH DINH DNG

[CHT]/MU KHNG KHONG GIAN

TNG CAO SAU N BO NHU M
 CHC NNG LC MU

MU MAO MCH NHIU VI KHUN

RUT

XOANG TM

1% VK THC BO (TB KUPFFER)

VT QUA
 CHC NNG BI TIT MT

TT C TB GAN MT

TIU QUN MT

NG MT CH NG MT LN
 BI TIT BILIRUBIN
GLOBIN
HEMOGLOBIN
HEM BILIVERDIN

PROTEIN
BILIRUBIN T DO BILIRUBIN

A. GLUCURONIC (80%)
HP THU (GAN) TAN TRONG
SULFAT (10%)
NC
CHT KHC
 CHC NNG CHUYN HO
1. CHUYN HO CARBOHYDRAT
GIP N NH NG HUYT TO GLYCOGEN

THU PHN
GLYCOGEN

NG PHN

TN TO
NG
 CHC NNG CHUYN HO(TT)

2. CHUYN HO PROTEIN
ALBUMIN
TI CN THIT CHO C TH
1 PHN
GLOBULIN

FIBRINOGEN

FERRITIN &
PROTHROMBIN
 CHC NNG CHUYN HO(TT)
3. CHUYN HO LIPID

BTA A.BO
LIPID GAN NNG LNG

CHOLESTEROL,

PROTEIN & PHOSPHOLIPID,

CARBOHYDRAT LIPOPROTEIN
 Thnh phn cc lipoprotein
Lipoprotein Chylomicron VLDL LDL HDL
T trng (g/ml) 0.93 0.95-1.006 1.019-1.063 1.063-1.210

ng knh * 800 5000-300 216 74-100

Thnh phn:
+ protein % <2 8 22 50
+ lipid % 98 92 78 50

Lipid chnh Triglycerid Triglycerid Cholesterol Cholesterol

Chc nng Vn chuyn Vn chuyn Vn chuyn Vn chuyn
chnh triglycerid triglycerid cholessterol cholessterol t
ngoai sinh ni sinh n t chc t chc ngoai
ngoai vi tiu th vi v gan
Ngun gc Rut Gan Chuyn ha Rut
ca VLDL Gan
 CHC NNG KHC

D TR VITAMIN & MUI KHONG

A 10 THNG
VITAMIN
D 3 4 THNG

B12 1 VI NM

MUI KHONG FERRITIN

Na, K, Mg,
 CHC NNG KHC

NG MU TT C CC YU T

II, VII, IX, X (VITAMIN K)

KH C NI SINH: H202, BILIRUBIN,

NH4,

NGOI SINH: KHNG SINH,

THUC NG,
 Tham gia hp thu Calci

Tin vitamin D3 biu b da

(7-Dehydrocholecalciferol)

Tia cc tm (nh sng mt tri)

Vitamin D3 (Cholecalciferol)

25-Hydroxylase (GAN)

25-Hydroxycholecalciferol
(Calcidiol)

1-Hydroxylase (THN)

1,25-Dihydroxycholecalciferol (Calcitriol)
 LNG GI
CU 1: PEPSINOGEN C BI TIT NHIU NHT GIAI AN
NO SAU Y?

a. Tm linh (*)

b. D dy .

c. Tm linh v d dy.

d. Rut
CU 2: DY CM GIC HNG TM CA BI TIT NC BT
L:

a. Dy IX v thng nh (*)

b. Dy X v thng nh

c. Dy IX v dy X

d. Dy V v dy X
CU 3: YU T KCH THCH BI TIT HCO3- D DY?

a. Prostaglandine I2 (*)

b. Histamin.

c. Acetylcholin.

d. Gastrin
CU 4: YU T LIN QUAN TRONG IU HA BI TIT MEN
CA TY:

a. Tnh acid cao, cholecystokinin, nang tuyn

b. Tnh acid cao, secretin, ng tuyn

c. M- sn phm tiu ha protein, cholecystokinin,

nang tuyn (*)

d. M- sn phm tiu ha protein, secretin, nang tuyn

CU 5: CHT NO SAU Y VA L MEN TIU HA VA L
TC NHN XC TC PHN NG?

A. PEPSIN

b. Trypsin (*)

c. Enteropeptidase

d. Chymotrypsin
CU 6: SNG CO THT D DY DO I XY RA KHI NO?

a. D dy trng.

b. C tn hiu lin quan n n ung.

c. ng huyt gim (*)

d. Kch thch dy thn kinh X

CU 7: CC CHT C TC DNG C CH C HC D DY,
CHN CU NG:

a. Cholecystokinin (*)

b. GIP (Gastric inhibitory peptid) (*)

c. Secretin (*)

d. Motilin.
CU 8: VITAMIN B12 SAU KHI C HP THU T NG TIU HA
S C D TR TRONG C QUAN NO?

a. Ty xng.

b. Ty tng

c. Lch.

d. Gan. (*
)
CU 9: MT NGI KHNG NUT C NC BT LU
NGY, C TH S MT MT LNG NG K:

a. Na+ v Cl-.

b. K+ v HCO3 . (*
-
)
c. Ca++ v phosphat.

d. Nc v men tiu ha tinh bt chn.

CU 10: C S IU TR LOT D DY- T TRNG:

a. Dng thuc khng Histamin H2.

b. Dng thuc khng Muscarinic.

c. Tt nht l dng thuc c ch bm H+- K+- ATPase.

(*)
d. Gim yu t ph hy, tng yu t bo v.
CU 11: CC YU T SAU Y C TC DNG KCH THCH BI
TIT ACID HCL CA D DY, NGOI TR:

a. Histamin.

b. Acetylcholin.

c. Gastrin.

d. Secretin. (*)
CU 12: HP THU LIPID, CHN CU SAI:

a. C hiu qu nh to micelles vi mui mt.

b. Phn ln lipid trong thc n c hp thu thng

vo tun hon mu v tnh mch ca. (*)

c. Ch yu l monoglycerid, acid bo.

d. 80- 90% dng Chylomicron.