Kuliah Imun Skin Integumen

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PERAN SISTEM IMUN

DALAM INFEKSI KULIT


dr.Budi Darma
Fakultas Kedokteran
Universitas Malahayati
SISTIM IMUN

NON SPESIFIK SPESIFI


K

FISIK/ LARUT SELULER HUMOR SELULER


MEKANIK AL SEL T
SEL B
KULIT B ASAM LAMBUNG-FAGOSIT : Th1 Th2
I

SELAP
O LISOZIM MONOLUKLEA
K Ts
UT I INTERFERON R
LENDIR M PMN Td
I AS NEURAMINIK
SILIA A
BATUK DAN LAIN-LAIN -SEL NOL : NK Tc
K
BERSIN H
U KOMPLEMEN
INTERFERON -SEL
M
O
R MEDIATOR :
A C REACTIVE PROTEIN
BASOFIL,
L (CRP) MAST 2
TROMBOSIT
Skin and mucous
membranes
Anatomical barrier (epidermis, dermls)
Unsaturated fatty acids: anti-bacterial
- sebaceus glands
- skin commensals:Proplonicbacterlum acnes
Saturated fatty acid: fungistatic
Mucus :
- trap organisms
Epithelium:
- prevent penetration of large molecules
- Prevent entrance of pathogens

7
TERIMAKASI
H

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