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Alergi

pada
saluran nafas
Conjunctivitis

Rhinitis

Clinical
manifestations
of
Urticaria
type I
hypersensitivity
Asthma

Gastroenteritis
sensitization

B
IL-4 Th2

IgE
immediate reaction
mestcel

late reaction

eosinofiel
Figure 1. (click image to zoom) Biosynthesis of arachidonic acid and the
cyclooxygenase (COX) pathway. HPETE = hydroperoxyeicosatetraenoic acid;
NSAIDs = nonsteroidal anti-inflammatory drugs.
Step-wise diagnosis of allergy
Selective Symptomatic
measurement therapy
of specific IgE Allergen
Probable in blood avoidance
allergy
Immunotherapy

Anamnesis
Allergy ? Physical
examination

positive
Possible
allergy Allergen panel
in skin testing
or Search for
other causes
Multi-allergen
Plebani, 2003 screening test negative

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