14 - Quiz

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Postgraduate Quiz

Instructions
All slides carry equal marks
There is no negative marking
Each slide will be given 30 seconds to 1 minute
after reading out the question

All the Best!


Q1.
18 years female presented with high grade fever
She was a known case of HIV

PBF
Identify the abnormality
Advice Cytochemistry
Q2.
48 years presented with weakness & variable cytopenias
She was being treated for depression

Trephine biopsy
Identify the abnormality
Advice Confirmatory test
Q3.
15 years male presented with fever with chills

PBF
Identify the abnormality
Name the Vector
Q4.

HPLC graph from BioRad Classic

Identify the abnormality

What will be the expected clinical


phenotype?
Q5.
Identify the preparation
Enumerate 2 conditions where the test may be positive
Q6.

64 year male with


splenomegaly.
Interpret the flow cytometry
Suggest a molecular
confirmatory test for this
disease?
Q8.

Describe the morphology of the cell in the peripheral blood film.


Mention 2 conditions where this can be seen
Q9.

Normal Patient

Spot the abnormality

Name 2 conditions where the


A B abnormality can be seen
Methemoglobin levels:
7.5% & after blood transfusion- 0.3%

?
Father (Case II)

Son (Case I )

OxyHb is capable of reversible oxygenation; its heme iron is in the


reduced (or ferrous) state
MetHb: Heme oxidizes spontaneously & is incapable of reversible
oxygenation
Q10.
21 years presented with gum bleeds & skin nodule
Blood counts showed increased TLC with thrombocytopenia

BM aspirate
1. Suggest possible diagnosis
2. Suggest associated
cytogenetic abnormality
2 year male presented with epistaxis Q6.
Coagulogram: PT- 13 sec, APTT-27 secs, N platelets
Platelet aggregation

Physiological Agonists
ADP
10mM
Collagen
2mg/ml Epinephrine
10mM Arachidonic acid
0.5mM

What is the diagnosis?


What will you find in a finger prick smear
What is the mode of inheritance of the condition?
Q 10.

Name any 2 agents


that can be used for
decalcification of bone
marrow biopsies.
Q 11.

Kidney biopsy from a 33 yr


female with seizures and
acute renal failure following
fever for a day.

What is the diagnosis?


What will the PT & PTTK
results?
Mention one therapeutic
modality.
Two siblings ages 3 & 5 years presented with Q 12.
pallor and mild hemolytic facies
BM was done to investigate cause of anemia

BM aspirate

Descibe the BM findings


Any confirmatory tests?
Q 13.
6 months child presented with progressive anemia and splenomegaly
Screening for thalassemia was negative

Trephine biopsy

Descibe the findings


Any special stains?
Q 14.
13 yrs male presented with fever & echymosis for 3 days
Blood cell counts showed anemia, leucocytosis and thrombocytopenia

Describe the BM findings and interpret the MPO stain

BM MPO
Q 15.

Describe the BM aspirate finding

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