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Improved Survival Among Icu-Hospitalized Patients With Community-Acquired Pneumonia by Unidentified Organisms: A Multicenter Case-Control Study
Improved Survival Among Icu-Hospitalized Patients With Community-Acquired Pneumonia by Unidentified Organisms: A Multicenter Case-Control Study
Improved Survival Among Icu-Hospitalized Patients With Community-Acquired Pneumonia by Unidentified Organisms: A Multicenter Case-Control Study
SIGIT ANANDA
1407101030284
Mortality and
Social cost
morbidity
Better
Early outcome?
antibiotic
Severe CAP &
Antibiotic
combination
Worst
Objective
Primary Objective
The primary objective of the present study was to
compare mortality between two cohorts of patients
diagnosed with severe CAP in different time periods
and admitted to the intensive care unit (ICU).
Secondary Objective
The secondary objective was to determine whether
changes in antibiotic policies were associated with
different outcomes.
Material and Methods
The CAPUCI I33 hospitals
from 2000 to 2002 (n=529)
Prospective The CAPUCI II 2008-2015
Cohort (n=616)
Inclusion criteria
CAPUCI 1
Severe CAP was defined as pneumonia that required ICU admission
following Infectious Diseases Society of America/American Thoracic
Society (IDSA/ATS) indications
Exclusion criteria
CAPUCI II
Patients with severe chronic illness in whom pneumonia was an
expected terminal event (do not resuscitate or intubate orders)
Patients diagnosed with healthcareassociated pneumonia or with a
no-cardiopulmonary resuscitation indication
Immune compromise