AMINO ACID &

PROTEIN STRUCTURE

Veterinary Biochemistry
- Nov 7 & 14, 2013

by:
drh. Aris Purwantoro, M.Si.
Dr. drh. Aris Haryanto, M.Si.
 Zwitterion
Amino acid exists as a dipolar ion.
-COOH loses H+, -NH2 gains H+.

Actual structure depends on pH.

 I. II.

Proteinogenic
Amino Acids

III. IV. V.

For each amino acid, the illustration

names:
o Membership of structural classes IVII
o Name and abbreviation, formed from
the first three letters of the name.
o The one-letter symbol introduced to
save space in the electronic
processing of sequence data. VI. VII.
o A quantitative value for the polarity of
the side chain (bottom left; 10.3 for
histidine).

The more positive this value is, the

more polar the amino acid is.
Biological functions (1)
Biological functions (2)
 Protein Functions
1. Establishment and
maintenance of structure
eg: collagen, histon, ceratin,
elastin, fibroin
2. Transport
eg: hemoglobin, prealbumin,
ion channel, myoglobulin,
albumin
3. Protection and defense
eg: immunoglobulin, thrombin,
fibrinogen
4. Control and regulation
eg: hormone, hormone receptor
5. Biocatalysis
eg: enzymes, trypsin,
ribonuclease
6. Movement
eg: actin, myosin, tropomyosin
7. Nutrient and storage
eg. ovalbumin, casein, ferritin
Secondary structure
Beta pleated sheet
Tertiary structure
Quaternary structure
Biological functions (1)
Biological functions (2)
. . . matur nuwun