Animal Biotechnology

Moises Von Rosauro R. De Gracia

MAEd Science
Tarlac Agricultural University
Animal Biotechnology
Biotechnology Innovation Organization (BIO) defines animal
biotechnology as provider tools for improving human and animal
health and welfare and increase livestock productivity.
Also, they improves the food we eat meat, dairy, and poultry
products.
Furthermore, they enhance the ability to detect, treat, and prevent
diseases.
Mohamed Ali of University of Hargeisa defines biotechnology as the
use of living organisms and their components in Animal, food and
other industrial processes.
Fourteen month-old genetically engineered (biotech) salmon (left) and standard salmon
(right).
Biotechnology Timeline

1. Ancient biotechnology- early history as related to food and

shelter; Includes domestication

2. Classical biotechnology- built on ancient biotechnology;

Fermentation promoted food production, and medicine.

3. Modern biotechnology- manipulates genetic information in

organism; Genetic engineering
Goal of Animal Biotechnology

Improve animals or the products they produce

Animal Cloning
Improvement animal Health.
Artificial Insemination
In vitro fertilization
Embryo Transfer
Multiple Ovulation
Application of Animal Biotechnology

The pioneering experiment of palmiter and co-workers, made in

1983, the giant mice were obtained over-expressing rat GH gene
fused to mMT promoter.
 The transgenic fish were produced transferring Growth hormone
(GH) gene
The first transgenic animal to be commercialized.
Transgenic Salmon can grow 3 times larger than wild type Salmon.
Can grow up to 6 times faster than wild type fish
 Transgenic Cattle
Dairy cows carrying extra copies of two types of casein genes produce
13% more milk protein.
Currently, no transgenic animal or animal product is approved by the
FDA or USDA for human consumption
Disease Resistant
Increased disease resistance can be achieved by introducing resistance-
conferring gene constructs into animals or by depleting a susceptibility
gene from the animal.
Vaccines
Vaccination is the most effective strategy for the control of disease in
human, poultry and other farm animals
The recombinant vaccine contain either a protein or gene coding for
protein of a pathogen origin that is immunogenic
 Livestock Pharming
Producing therapeutic proteins in transgenic farm animals is sometimes
called biophraming/molecular pharming
Therapeutic proteins are used to treat human diseases. They include
hormones, antibodies, vaccines, growth factors and blood clotting
factors.
Disease Resistant
Increased disease resistance can be achieved by introducing resistance-
conferring gene constructs into animals or by depleting a susceptibility
gene from the animal.
Vaccines
Vaccination is the most effective strategy for the control of disease in
human, poultry and other farm animals
The recombinant vaccine contain either a protein or gene coding for
protein of a pathogen origin that is immunogenic
 Scientific Reports on Animal
Biotechnology
Etienne Bilgo, et.al. conducted a research on improved efficacy of
an arthropod toxin expressing fungus against insecticide resistant
malaria-vector mosquitoes (submitted Jan. 18, 2017, published June
13, 2017)
The research focuses on the fight against malaria-carrying mosquito
that is resistant on insecticide, specifically the wild-caught mosquito.
The said research was already conducted years ago, but the
mosquito seems to be more and more resistant to the insecticide.
So they used an arthropod toxin that creates lethal fungus to
malaria-carrying mosquito
An excerpt from their research.
Thank you