Hiperlipidemia

FKK/A KELOMPOK 4 :
1. Rostika Imroatun M (20144203A)
2. Nailul Afnia (20144221A)
3. Sukini (20144225A)
4. Febrilia Islami Putri (20144230A)
5. Zainab (20144235A)
DEFINISI
FAKTOR RESIKO
PATOFISIOLOGI
MANIFESTASI KLINIK
DIAGNOSIS
ALGORITMA
 KASUS
B.C., a 56-year-old man, experienced acutechest pain 3 months ago and was admitted to the local
hospital with a diagnosis of unstable angina. His only knownmedical problem was hypertension
treated with enalapril10 mg every day. His lipid profile on admission was as follows:
Total cholesterol, 235 mg/dL
HDL-C, 30 mg/dL
LDL-C, 165 mg/dL
TG, 300 mg/Dl
He underwent a cardiac catheterization, which revealeda 90% stenotic lesion in his left anterior
ascending artery. Adrug-eluting stent was placed without difficulty. He was subsequently
discharged on simvastatin 40 mg every eveningat bedtime, ezetimibe 10 mg every day,
acetylsalicylic acid325 mg every day, clopidogrel 75 mg every day, metoprolol100 mg twice daily,
and enalapril 10 mg every day.Today, he weighs 220 pounds, is 6 feet tall (ideal bodyweight, 140 to
185 pounds), and has a waist circumferenceof 42 inches. He has lost 10 pounds since his diagnosis
ofunstable angina by following a low-fat diet and an exerciseprogram. He swims 1 mile three times
a week without symptoms of cardiac ischemia, and he drinks two glasses of wineeach evening with
dinner. His father died at age 58 of anMI (lipids unknown). He has never smoked. Pertinent physical
findings include a BP of 148/90 mm Hg, heart rate thatis 60 beats/minute and regular, arcus senilis,
carotid pulsesequal without bruits, and chest clear to auscultation withoutcardiomegaly. Laboratory
tests disclose normal TSH levels,normal renal and liver function, and a fasting glucose levelof 120
mg/dL. His urinalysis was normal. The lipid profilewhile taking the above regimen is as follows:
Total cholesterol, 143 mg/dL
TG, 210 mg/dL
HDL-C, 33 mg/dL
LDL-C, 68 mg/dL
 SUBJEK
Nama : Tn. B.C. (56 tahun)
Berat badan 220 pound, Tinggi 6 kaki, Lingkar pinggang 42
inchi.
Keluhan : mengalami nyeri dada akut 3 bulan yang lalu dan
dirawat dirumah sakit setempat dengan diagnosis angina
yang tidak stabil
Kebiasaan : Setelah didiagnosa angina tidak stabil dia
mengikuti diet rendah lemak dan program olahraga. Dia
berenang 1 mil tiga kali seminggu tanpa gejala iskemia
jantung, minum dua gelas anggur setiap malam dengan
makan malam, tidak perokok berat
Riwayat keluarga : Ayahnya meninggal umur 58 tahun
Karena Myocardial Infraction (MI) (lipid unknown)
Diagnosa medis yang diketahui : hipertensi
 Riwayat pengobatan
enalapril 10 mg (setiap hari)
Simvastatin 40 mg (setiap malam pada waktu
tidur)
ezetimibe 10 mg (setiap hari)
Asam asetil salisilat 325 mg (setiap hari)
Clopidogrel 75 mg (setiap hari)
Metoprolol 100 mg (2x sehari)
 OBJEK
Kateterisasi jantung : lesi stenotik 90%
TEKANAN DARAH : 148/90 mm/Hg
Denyut jantung 60/menit
Tsh normal, fungsi ginjal dan hati normal,
urinisnya normal
Kadar glukosa puasa 120mg/dL
 Lanjutan
Pemeriksaan (saat masuk RS) Nilai Normal
Total kolesterol 235 mg/ dL < 200 mg/ dL
HDL 30 mg/ dL > 60
LDL 165 mg/ dL <100
Trigliserida 300 mg/ dL <150

Pemeriksaan (Setelah pengobatan ) Nilai Normal

Total kolesterol 143mg/ dL < 200 mg/ dL
HDL 33 mg/ dL > 60 mg/ Dl
LDL 68 mg/ dL <100 mg/ dL
Trigliserida 210 mg/ dL <150 mg/ dL
 ASSESMANT
PROBLEM SUBJEK OBJEK TERAPI DRP
MEDIK

Angina Mengalami Clopidogre,

Nyeri Dada Metoprolol,
Akut asam Asetil
Salisilat

Hyperlipidemia Total cholesterol 143 mg/dL Simvastatin

TG, 210 mg/dL Dan Ezetimibe
HDL-C, 33 mg/dL
LDL-C, 68 mg/dL

Hypertensi 148/90 mmHg Enalapril dan

Metoprolol
 PLAN
Non farmakologi
Kurangi konsumsi garam

Farmakologi