Histologi reproduksi pria

Afiana Rohmani

BLOK 5 FK UNIMUS,
2014
http://www.uh.edu/~tgill2/image010.jpg
Male Reproduction System
ANATOMI , Consists of:
A pair of testes
A network of excretory ducts
epididymis
vas deferens
ejaculatory ducts
Seminal vesicles
Prostate
Urethra
Penis
Male Reproduction System
Functions
To produce, maintain and transport
sperm (the male reproductive cells) and
protective fluid (semen)
To produce and secrete male sex
hormones responsible for maintaining
the male reproductive system
TESTIS

Testes / testicles
(Gonads)
Produce sperm
(Spermatogenesis)
Sperm production
begins at puberty and
continues throughout
the life of a male
 Duct System
Epididymis
Sperm mature in
epididymis
Vas Deferens
Transports
mature sperm to
the urethra
Ejaculatory ducts
empty into the
urethra
 Seminal vesicles
Attached to vas
deferens
Produce a sugar-
rich fluid
(fructose) that
provides energy
to sperm
 Prostate Gland
Makes fluid
 Urethra
Tube that carries
urine from the
bladder to outside
of the body
Also carries
semen out of the
body
TESTIS
Diselimuti jar.ikat = tunika albuginea
Dibagi kompartemen2 =Lobulus testis
Tiap lobulus t.d Tubulus seminiferus
TubSeminiferus terpendam dalam jar.ikat
longgar yang terdiri dari
pd , pl, saraf dan sel interstitial/sel Leydig.
 Tub seminiferus spermatogenesis
Sel Leydig hormon androgen testis.
Tubulus seminiferus
Tubulus brkelok-kelok, brawal dari saluran
buntu.
Muara lumen menyempit berlanjut ke
tubulus rektus rete testis duktuli
efferentes epididimis.
Tubulus seminiferus
Lapisan :
Jar.ikat fibrosa
Lamina basal td sel-sel mioid (sel
otot polos)
Epitel germinal
Sel epitel : td 2 jenis sel :
Sel sertoli = sel penyokong
Sel spermatogenik = td 4 lapisan
spermatogenesis spermatozoa.
 spermatogenesis
development of sperm from spermatogonia
multiple division two times meiotic

1. Spermatogonia type A B
2. Primary Spermatocytes (44+XY), (>>)
3. Secondary Spermatocytes (22 +X) or(22+Y)
4. Spermatid
Spermiogenesis = maturation of spermatid into
sperm spermatozoa
Spermatogenesis
spermiogenesis
 Sel sertoli
Sel penyokong
Menunjang, melindungi, mengatur nutrisi
spermatozoa yg sedang brkembang.
membentuk sawar testis-darah
Fagositosis
Msekresi protein ABP (Androgen Binding Protein) ,
(di bawah kendali testosteron &FSH). proses
spermatogenesis.
 Jaringan interstitial testis
Merupakan jaringan ikat.
Kaya pd, pl, saraf . Mngandug sel Leydig
Sel Leydig = mhasilkan hormon testoteron.
Hormon testoteron proses spermatogenesis,
perkembangan ciri kelamin sekunder,
Di bawah kendali dari hormon LH dari hipofisis.
Aktif saat pubertas.
Sperm maturity and transport
pathway
Tubuli recti
rete testis intratestis
Ductuli efferentes
Epididymis
Ductus deferens
Ejaculatory duct
Tubuli recti et rete testis, tubuli
efferentes
Cuboideal cells and sertoli, surrounded by
lymphatic channels, blood vessels and
Leydig cells

no spermatogenic cells, only spermatozoa

cell
 Epididymis
Ductuli efferentes ductuli epididimis
Ductuli epididymis Head :
columnar epitheluim with stereocilia and cilia
smooth muscle layer
Ductus epididymidis in body & tail
highly coiled one tubule - 4-6 m long
columnar epithel with stereocilia
two layers of smooth muscle thicker
function
Maturation, storage, transport
Ductus defernes (Vas deferens)
pseudostratified columnar epitel
lamina propria
3 layers of smooth muscle (L, C, L)
Ampula : thicker epithel
Seminal vesicles (Glandulae
vesiculosae)
folded mucosa with pseudostratified
epithel , with secretorius glands.
smooth muscle layer (C+L)
Activation regulated by testoteron.
function: 50-70% of seminal fluid
Contain fructose
 Prostate
30-50 tuboalveolar glands in fibromuscular stroma
tuboalveolar epitel silindris bertingkat.
3 regions of glands
Central zone
Transition zone BPH ( Benign Prostate
Hiperplasia)/ hiperplasia jinak prostat
Peripheral zone
 Penis
three masses of erectil tissue
2x corpora cavernosa
1x corpus spongiosum (corpus cavernosa
urethra)
a. profunda a. nutritif & a.helicinae
communicating blood spaces (sinuses) surrounded
by connective tissue (trabekula)
artery -> sinus -> vein
dilatation of artery compress vein, sinuses fill with
blood -> erection occurs
 urethra
1. Pars prostatika , ep transisional
2. Pars membranosa, ep silindris bertingkat sfingter
uretra eksterna
3. Pars bulosa letak di korpus
4. Pars pendulosa spongiosum (pars
cavernosa)

Dilapisi epitel silindris bertingkat.

, Pars pendulosa = squamus
Littre glands mucosa urethra
 TERIMA KASIH,
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