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NCI Workshop On Advanced Technologies in Radiation Oncology: Cervix
NCI Workshop On Advanced Technologies in Radiation Oncology: Cervix
Pt A 85 Gy,
VSD 110 Gy,
Cervical os 150-200 Gy
Radiotherapy for Cervix Cancer: An
Important Paradigm
• Dose Limiting toxicity
– Small Bowel: < 45 Gy
– Rectum: < 75 Gy
– Bladder: < 75 Gy
Chemo?
5/132 with PET + Pelvic LN’s failed. 1/33 with PET + PA LN’s failed.
RFS by PET
Cervix Cancer
• Cervix/Vagina is mobile
• Variable filling of bowel and
bladder
• ITV used in post hysterectomy
setting in RTOG 0418
No Randomized Trials!
Cervix: IMRT/IGRT
No Randomized Trials!
• Dutch Trial
– RT and hyperthermia +/- chemo
Dimoupoulos et al IJROBP
66(1):83, 2006
Promising Technologies in Cervix Cancer