• Blood substitutes aim to replicate one particular job of real blood: supplying oxygen to tissues. In other words, the goal is to find an alternative to oxygen-carrying redblood cells that could be used for transfusions. Why’s it important/how does it benefit? • Blood substitutes are more robust than regular blood and can withstand more harsh environments such as not requiring refrigeration and can be used in the pre-hospital environment. Synthetic blood delivers oxygen to the body faster than realblood which can limit bodily injury, particularly during heart attack. Advantages • The main advantage with artficial hearts is that they are not rejected by the body's immune system. This is because they're made from metals or plastics, so the body doesn't recognise them as 'foreign' and attack in the same way it does with living tissue Disadvantages • Surgery to fit an artificial heart can lead to bleeding and infection. • Artificial hearts don't work as healthy as natural ones-parts could wear out or the electrical motor could fail. • Blood flow doesnt flow through artificial hearts as smoothly, which can cause blood clots and lead to strokes. • The patient has to take drugs to thin their blood and make sure this doesn't happen, which can cause problems with bleeding if they're hurt in an accident. Current research on the topic Conclusion