Professional Documents
Culture Documents
001 Breast Cancer Presentation
001 Breast Cancer Presentation
001 Breast Cancer Presentation
CANCER
introduction
Cancer is a class of diseases in which a
group of cells display uncontrolled
growth (division beyond the normal
limits), invasion (intrusion on and
destruction of adjacent tissues), and
sometimes metastasis (spread to other
locations in the body via lymph or
blood). These three malignant properties
of cancers differentiate them from
benign tumors, which are self-limited,
and do not invade or metastasize.
Breast cancer occurs when abnormal cells
grow out of control in one or both breasts.
They can invade nearby tissues and form a
mass, called a malignant tumor. The cancer
cells can spread (metastasize) to the
lymph nodes and other parts of the body. It is
the leading cause of death in women 40-44
years old and the second most common
killer of women after lung cancer. Heightened
awareness of breast cancer risk in the past
decades has led to an increase in the
number of women undergoing
mammography for screening, leading to
detection of cancers in earlier stages and a
resultant improvement in survival rates.
Current statistics indicate that
over an entire lifetime (birth to
death), a woman’s risk for
developing cancer is 1in 8. When
broken down by age 39 years is 1
in 209, and it increases to 1 in 24
by age 59 years. Although breast
cancer in women is a form of
cancer, male breast cancer does
occur and accounts for about 1%
of all cancer deaths in men.
In the Philippines, breast cancer
accounts for 16 percent of the
50,000 cases of the dreaded
disease. It is also the leading
cause of cancer among women in
the country, accounting for 28%
of the total cases, followed by
cancer of the cervix, ovary,
thyroid and lung.
Treatment options for breast cancer may involve
surgery (removal of the cancer alone or, in some
cases, mastectomy), radiation therapy, hormonal
therapy, and/or chemotherapy. With advances in
screening, diagnosis, and treatment, the death
rate for breast cancer has declined by about 20%
over the past decade, and research is ongoing to
develop even more effective screening and
treatment programs. Staging systems have been
developed to allow doctors to characterize the
extent to which a particular cancer has spread and
to make decisions concerning treatment options.
Breast cancer treatment depends upon many
factors, including the type of cancer and the extent
to which it has spread.
RISK
FACTORS
Family history: Having a 1st-degree relative
(mother, sister, daughter) with breast cancer
doubles or triples risk of developing the cancer,
but breast cancer in more distant relatives
increases risk only slightly. When ≥ 2 1st-
degree relatives have breast cancer, risk may
be 5 to 6 times higher. A woman's risk of breast
cancer is higher if her mother, sister, or
daughter had breast cancer. The risk is higher if
her family member got breast cancer before
age 40. Having other relatives with breast
cancer (in either her mother's or father's family)
may also increase a woman's risk.
Breast cancer genes: About 5% of women with
breast cancer carry a mutation in one of the 2
known breast cancer genes, BRCA1 or BRCA2.
If relatives of such a woman also carry the gene,
they have a 50 to 85% lifetime risk of developing
breast cancer. Women with BRCA1 mutations
also have a 20 to 40% lifetime risk of developing
ovarian cancer; risk among women with BRCA2
mutations is increased less. Women without a
family history of breast cancer in at least 2 1st-
degree relatives are unlikely to carry this gene
and thus do not require screening for BRCA1 and
BRCA2 mutations. Men who carry a BRCA2
mutation also have an increased risk of
developing breast cancer. Changes in certain
genes increase the risk of breast cancer.
These genes include BRCA1, BRCA2,
and others. Tests can sometimes show
the presence of specific gene changes in
families with many women who have had
breast cancer. Health care providers may
suggest ways to try to reduce the risk of
breast cancer, or to improve the
detection of this disease in women who
have these changes in their genes.
Personal history: Having
had in situ or invasive
breast cancer increases
risk. Risk of developing
cancer in the
contralateral breast after
mastectomy is about 0.5
to 1%/yr of follow-up.
Reproductive and menstrual
history:
Women who went through
menopause after age 50
are at an increased risk of
breast cancer.
Breast changes: History of fibrocystic changes
that require biopsy for diagnosis increases risk
slightly. Women with multiple breast lumps but no
histologic confirmation of a high-risk pattern
should not be considered at high risk. Benign
lesions that may slightly increase risk of
developing invasive breast cancer include
complex fibroadenoma, moderate or florid
hyperplasia (with or without atypia), sclerosing
adenosis, and papilloma. Risk is about 4 or 5
times higher than average in patients with
atypical ductal or lobular hyperplasia and about
10 times higher if they also have a family history
of invasive breast cancer in a 1st-degree relative.
Increased breast density seen on screening
mammography is associated with an increased
risk of breast cancer
clusive evidence about the effect of a particular diet (eg, one high in fats) is lacking. Obese postmenopausal women are at increased risk, but there is no evidence that dietary modification reduces risk. For
EARS:
With medium
sized pinna
EYES: Ears are lined
With round NOSE: with the outer
eyes, Shaped canthus of the
moderately high MOUTH AND eye
symmetrical
bridge THROAT: Ear canal
With white
Nostrils are Lips and moderately
sclera
patent oral mucosa moist with
With slightly
With septum is slightly earwax
pale conjunctiva
deviation pale No odor
With presence
No discharge With slightly
of eye bag
noted yellowish
teeth
With moist
oral
membranes
SKIN:
Brown in
complexion
With good
skin turgor
With cold
clammy skin
With fine
hair in
extremities
Neck:
No scars
ACTIVATION
GENOTOXIC MECHANISMS:
NON-GENOTOXIC MECHANISMS:
>DNA ADDUCTS
>INFLAMMATION
>CHROMOSOME BREAKAGE,
>IMMUNOSUPRESSION
FUSION, DELETION,
>REACTIVE OXYGEN AND NITROGEN SPECIES
MISSEGREGATION,NON-
>EPIDEMIC SILENCING
DISJUNCTION
>ACTIVATION OF PROTOOCCOGENES
>ALTERED DNA
>LOSS OF GENE SUPPRESSOR BLOCKADE
>ABNORMAL ONCOGENE
AMPLIFICATION/MUTATION TRANSFORMATION
>GENE SUPPRESSOR
BLOCKADE(BRCA1,BRCA2,P53)
promotion phase
ABNORMAL DNA AND CELL REPLICATION
TISSUE NECROSIS/METASTASIS
INVASIVE CANCER
BLOOD CHEMISTRY
Examination Results Normal Values Findings
Protime 13.3 sec 11-14 sec NORMAL
INR 0.99 0.8-1.2 NORMAL
% Activity 103% 70-120% NORMAL
PT Control 13.2 sec. 11-14 sec NORMAL
PTT 27.8 sec 27-34 sec NORMAL
INR 1.08 0.8-1.2 NORMAL
PTT Control 33.6 sec 27-34 sec NORMAL
COAGULATION
FACTORS
URINALYSIS
Color Yellow
Appearance Slightly Hazy
Pus Cells 60-70/hpf
Specific 1.010
RBC 10-12/hpf
Gravity
pH 8.0
Glucose Negative Amorphous Urates FEW
Protein +2 Bacteria FEW
Ketones Negative
Bilirubin Negative
Urobilinogen Normal
Blood/Hgb +1
Nitrite Negative
Leukocytes +3
MEDICAL
MANAGEMENT
DIAGNOSTIC IMAGING REPORT:
Chests PA view:
There are no active lung infiltrates.
The heart is not enlarged. Aorta is tortuous.
The cp sulci, diaphragm and bony thorax are
unremarkable.
MACROSCOPIC AND MICROSCOPIC EXAMINATION
Cytology reveals malignant cells singly and in
overlapping sheets with large, irregular, hyperchromatic
nuclei surrounded by scant cytoplasm. The background
shows moderate red blood cells.
FINAL PATHOLOGICAL DIAGNOSIS:
FNAB, BREAST MASS
POSITIVE MALIGNANT CELLS
ECG: Normal Findings
DIAGNOSTIC
PROCEDURE
a) Self-examination - 90% of the breast masses are
discovered by the patient herself. From this manner,
self-examination appears as one of the most
important measures for the early diagnosis of breast
cancer, once it: allows the detection of small masses;
is an useful, convenient, profitable, advantageous
and opportune method: can be repeated as many
times as necessary; has no cost; is easy to be done;
its precision increases with practice.
Self-examination must be performed 7-8 days after
menstruation by every woman with more than 20
years old, in order to detect early changes in breast
parenchyma.
b) History - Verify the presence of risk factors and evaluate
the patient’s complaint
Risk Factors - sex (100 women: 1 men); familiar history;
adverse hormonal environment; other lesions on the breast
in the past
Presenting Complaint - lump - is the main complaint (70% of
the cases). Evaluate its consistence, mobility, growth,
changes with menstrual cycle, and if it is painless or not .
Nipple discharge - investigate spontaneous discharge,
which can be watery, serous or bloody. Remember some
medications can cause nipple discharge, such as
contraceptives and reserpine.
eczema - if it is important, unilateral and in the nipple
area, it can suggest the presence of malignancy in the
ductal system below the nipple.
pain - especially if after menopause and if unilateral.
other - erosion, retraction, enlargement, swelling,
redness, axillary mass and bone pain .
c) Physical Examination - Inspection of the breast is the first
step in physical examination and should be carried out with
the patient sitting, arms at sides and then overhead.
Abnormal variations in breast size and contour, minimal
nipple retraction, and slight edema, redness or retraction of
the skin can be identified. Asymmetry of the breasts and
retraction or dimpling of the skin can often be accentuated by
having the patient raise her hands overhead or press her
hands on her hips, in order to contract the pectoralis
muscles . Axillary and supraclavicular areas should be
thoroughly palpated for enlarged nodes with the patient
sitting. Palpation of the breast should be performed with the
patient both seated and supine with the arm abducted.
Every woman between 20-40 years must have her breasts
examined by a specialist every 2/3 years. After 40 years,
examinations must be annually , and in women with high-risk
for breast cancer, every semester
d) Cytology - Fine Needle Aspiration
(FNA) has a simple technique and a
high level of concordance with
hystopatological findings. The
cyto/hystopathologic relation is 83.4%,
but in malignant lesions this relation is
94.7%. It is important, however, to say
that FNA results are ONLY diagnostic
when concordant with clinical findings!
Axillary nodes can also be examined, in
order to stage disease.
e) Biopsy - It is the preferred isolated
diagnostic method before deciding
on a definite treatment. Delayed
biopsy must be preferred to frozen
biopsy, once it: allows patients to
accept their diagnosis, to decide on
their treatment, and even to look for
a second opinion. Trials have been
demonstrating that there is no
problem in delaying treatment for 1-2
weeks with this routine
Proposed
diagnostic
procedures
a) Mammography - It is the single reliable means of
detecting breast cancer before a mass can be palpated
in the breast ( it can detect microcalcifications smaller
than 1mm of diameter, and frequently associated with
malignant lesions).
Over then for screening, indications for mammography
are as follows: to evaluate each breast when a
diagnosis of potentially curable breast cancer has been
made; to evaluate a questionable or ill-defined breast
mass or other suspicious change in the breast; to
search for an occult breast cancer in a woman with
metastatic disease in axillary nodes or elsewhere; to
screen a group of woman with high risk for breast
cancer; to screen women prior to cosmetic operations or
prior to biopsy; to follow women who have been treated
with breast-conserving surgery and radiation.
Patients with a suspicious mass must have a
cyto/hystological exam made, despite mammographic
findings . Mammography IS NOT a substitute for biopsy.
b) Ultrasound - US can distinguish between
solid and cystic lesions , although it is less
sensitive than mammography in identifying
breast cancer, especially because neoplastic
areas are difficult to be differentiated from
normal parenchyma. On the same way, it is
difficult to differ from malignant and benign
characteristics. Isolated US can rarely detect
malignant lesions smaller than 1 cm or
microcalcifications. It is generally used to
evaluate young women’s (<35 years) breasts,
once mammograms are not indicated in these
cases.
drug study
NAME OF SPECIFIC MECHANISM SPECIFIC CONTRAINDICATI ADVERSE NURSING
DRUG ACTION OF ACTION INDICATION ON EFFECT CONSIDERATION
Skin: pruritus,
rash, diaphoresis
NAME OF SPECIFIC MECHANISM SPECIFIC ADVERSE NURSING
CONTRAINDICATION
DRUG ACTION OF ACTION INDICATION EFFECT CONSIDERATION
HEME:
bleeding,
platelet
inhibition with
higher doses
NAME OF SPECIFIC MECHANISM SPECIFIC ADVERSE NURSING
CONTRAINDICATION
DRUG ACTION OF ACTION INDICATION EFFECT CONSIDERATION
Subjective:
“Masakit ang aking Acute chest pain related to At the end of nursing Establish Nurse-client To gain trust and Goal was met.
dibdib” as verbalized by post operative surgery as intervention the client’s interaction better understanding Pain scale lessened
the client. evidenced by guarding pain will lessened. on patient’s condition from 7/10 to 4/10
behavior. Serve as baseline data
Objective: Take and record vital of the patient
sign
conscious and
coherent To prevent air
afebrile Check and regulate embolism and provide
with body malaise IVF hyration.
guarding behavior
with slight pain at left Environment has a
chest-pain scale of Provide therapeutic great impact on
7/10 (faces pain scale) environment. client’s health and
with limited range of wellness
motion Note pain including To rule out worsening
negative difficulty of the location, duration, of underlying
breathing frequency and condition/developmen
intensity. Reassess t of complications.
each time pain
occurs/is reported.
Provide comfort
measures such as: To avoid bed sores
and other
a. Repositioning every 4 complication and to
hrs. promote non-
pharmacological pain
b. Back massage. management.
Encourage adequate
rest period.
Assessment Diagnosis Planning Implementation Rationale Evaluation
Subjective:
“Hindi ako masyadong Impaired physical mobility At the end of nursing Establish Nurse-client To gain trust and better Client was able to
makagalaw kapag related to decreased muscle intervention the client will interaction understanding on perform activities
sumasakit ang dibdib ko” strength as evidenced by regain strength and be able patient’s condition without complaints
as verbalized by the client. limited body movements to increased mobility. Serve as baseline data of pain
and body malaise Take and record vital of the patient
Objective: sign
To prevent
contractures
b. Apply passive
ROM To reduce risk of
pressure ulcers.
Instruct patient to
change position side to
side every 4 hrs.
To maintain position of
Support affected body function
parts or joins using
pillows or foot
supports.
To prevent
Massage and stretch contractures and
extremities within the increase mobility of the
clients reached. extremities.
Instruct activities such
as:
a. socialize with patients To divert attention of
SO the patient and to
b. read newspaper enhance self concept
c. listening to music and sense of
d. Encourage independence.
participation in self
care.
Assessment Diagnosis Planning Implementation Rationale Evaluation
Subjective:
“Katatapos ko lang Disturbed body image At the end of nursing Establish Nurse-client To gain trust and better The patient was
operahan,nakakahiya na related to post surgical intervention the client will interaction understanding on able to understand
ang itsura ko’’ verbalized by procedure as manifested by be able to verbalize patient’s condition her situation
the client. irritability. understanding of body
images. Take and record vital Serve as baseline data
Objective: sign of the patient
Heath teachings
rendered such as: To prevent the spread
a. Proper hygiene of microorganisms
b. Increase protein To facilitate healing of
intake wound.
b. Avoid lifting heavy To prevent fatigue.
objects
d. Encourage daily To prevent further
wound dressing and complications and
use of antiseptic infection.
solutions.
DISCHARGE
PLANNING
DISCHARGE PLAN
Goals:
Achievements of activity level sufficient for basic self-care.
Disease process, treatment plan, and prognosis understanding.
Management to anxiety.
Meeting the require needs after discharge plan.
Importance compliance for medication.
Always perform exercises that will enhance the strength of the muscles
such as:
a) Wall hand climbing
b) Rod or broomstick lifting
c) Pulley tugging
d) Rope turning
Avoid lifting heavy objects.
Practicing deep breathing exercise.
Encourage to perform a breast self examination monthly.
Provide emotional and physical support to the patient.
Include family members in teaching the patient about self-care.
Let the patient report any unusual feelings of pain to the physician.
Provide proper body hygiene.
Use antiseptic solution in cleaning the wound.
Teach the patient how to empty the drainage reservoir:
a) Measure first the drainage if discharged with drain in place.
b) State observations that require contacting the physician/nurse
(sudden change in color of drainage, sudden cessation of
drainage and signs or symptoms of an infection).
c) Identify when the drain is ready for removal (usually when
draining than 30 mL for a 24 hour period).
Use warm water in taking a bath.
Encourage client for follow up check up to the physician (every 3
months for 2 years then every 6 months for up to 5 years then
annually)
Let the patient report any unusual feelings of pain to the physician.
Let your client perform a positive outlook in life. Be positive and
don’t be conscious about her body image.
DIET: can eat any kind of foods as tolerated by the patient
SEX: Once discharge in the hospital most patients are physically
allowed to engage in sexual activities
a) Just assume position which they are more comfortable
b) Can express affection such as: hugging and kissing
Normalize her activities of daily living such as: walking and caring
for her children if ever.
Presented by:
Pacia, derrick
Padua, genesis