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Ilham fajri

Amwal
Qurzatul aini
Ayu novita miza putri
Ayu zulfindri yana
Rizka mulyana
Nur aflah
Jamalul hikmah
Miranda febrian
Dicky nanda muzida
Dhiani putri ginting
Zery ananda
Description:
 Digoxin is obtained from the leaves of digitalis plant
(leaves are used as medicine strengthens the heart).
Digoxin helps make the heart beat stronger and with a
more regular rhythm.

composition:
 Each tablet contains 0.25 mg digoxin.

packaging:
 The bottle contains 100 tablets
 Box contains 10 strips of 10 tablets
mechanism action of digoxin:
Digoxin is a cardiac glycoside prototype from
Digitalis lanata. Mechanism of action of
digoxin in 2 ways, namely direct and indirect
effects. The immediate effect of improving the
strength of heart muscle contraction (positive
inotropic effect). This occurs by inhibition of
the enzyme Na +, K + -ATP ase and increase in
the inflow of calcium ions into the cell intra.
Indirect effect is the effect of digoxin on the
activity of the autonomic nervous and cardiac
sensitivity to neurotransmitters.
indication
 - Heart failure, supraventricular
arrhythmias (especially atrial fibrillation).
 - For congestive heart failure, atrial
fibrillation, atrial tachycardia and atrial
flutter proximal.
 - To treat congestive heart failure, is also
used to treat atrial fibrillation, atrial
arrhythmia (heart upper porch that allow
blood flow to the heart).
toxicity
 May occur anorexia, nausea, vomiting and
headache.
 Toxic symptoms in heart: multiform premature
ventricular contractions or unifocal, ventricular
tachycardia, AV desosiasi, sinus arrhythmia, atrial
tachycardia with varying degrees blokAV.
 Neurologic symptoms: depression, drowsiness,
weakness, lethargy, restlessness, vertigo, confusion
 and visual hallucinations.
 Disorders of the eye: mydriasis, photophobia, and a
variety of vision disorders.
 Gynecomastia, makulopopular skin rash or other
skin reactions.
THANK YOU

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