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Hipoksia - Berlian
Hipoksia - Berlian
Pembimbing:
dr. Erniody, Sp.An KIC M.Kes
Penyusun:
Berlian Purnamasari Setiono - 406152036
Poisoned tissue
HISTOTOXIC HYPOXIA
DEFINITION: Inability of the tissues to utilize oxygen inspite of
normal arterial PO2 and oxygen carrying capacity.
CAUSES:
• Cyanide poisoning (it inhibits cytochrome oxidases oxidative
process is inhibited).
• Narcotic overdosage (it inactivates the enzyme dehydrogenase
inhibition of tissue oxygenation).
• Beri-beri (it is deficiency of thiamine co-enzyme which is
required for many oxidative reactions).
TREATMENT:
• Methylene blue or nitrites. These convert hemoglobin met-
hemoglobin.
• Cyanide + met-hemoglobin cyn-met-hemoglobin (non-toxic
compound).
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