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Pathogenic Fungi
Pathogenic Fungi
Pathogenic Fungi
FUNGI
Group 21
Members of group:
oArinda Rifana Nabillah 1718011057
oC Byli Pandu Eka Putra 1758011010
oDaniel Christianto 1718011109
oElmarossa Dinda 1758011034
oFeby Aulia Hasanah 1718011007
oJesica Natalia 1718011018
oJihan Azita Maharani 1718011137
oMuhammad Panji Marga 1758011015
oZhovarina Isniarta 1758011044
Medical mycology
• field of medicine concerned with
the diagnosis, managements and
prevention of mycoses
MYCOSES
• Diseases caused by fungi
• Mode of infection:
– Inhalation
– Trauma
– Ingestion
– Rarely from person to person
• Toxicoses (poisoning)
• Allergies (hypersensitivity
reactions)
Mycoses are also among
the most difficult diseases
to heal.
Because…
• Fungi possess the biochemical ability
to resist the oxidative damage
perpetuated by T cells during cell-
mediated immune response
• Opportunistic fungi
True pathogens
• Have the ability to actively attack
and invade tissues
• Blastomyces dermatiditis
• Coccidiodes immitis
• Histoplasma capsulatum
• Paracoccidiodes brasiliensis
• Osteoarticular blastomycosis – a
condition where fungus spreads to the
spine, pelvis, cranium, ribs, long bones,
or subcutaneous tissues surrounding
joints.
•Patients with Cutaneous blastomycosis -
• painless lesions on the face and upper body.
COCCIDIOIDOMYCOSIS
• Treatment - Amphotericin B or
Ketoconazole
Systemic Mycoses Caused by
Opportunistic Fungi
-Hypertensitivity aspergillosis-
manifests as asthma
• Treatment
- solutions of antifungal imidazoles, such as
ketoconazole shampoos.
- topical applications of zinc pyrithione
- selenium sulfide lotions
- propylene glycol
Cutaneous and Subcutaneous
Mycoses
• Infection requires traumatic introduction of
fungal elements beneath the outer, dead
layers of skin.
CHROMOBLASTOMYCOSIS
• Toxicoses (poisoning)
• Allergies (hypersensitivity
reactions)
Toxicosis
• Mycotoxicosis – caused by eating
food contaminated with fungal
toxins only