Introduction of Clinical Biochemistry

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Introduction of

Clinical Biochemistry
The Function of Clinical
Laboratory
1. Supporting the diagnosis of
disease
2. Monitoring the course of the
disease (prognosis)
3. Monitoring therapy
(effectiveness of treatment)
4. Screening of the diseases or risk
factors
5. Check up (prevention)
6. Epidemiological studies
7. Supporting health research
The Clinical Laboratory

1. Chemistry
2. Hematology
3. Urine
analysis
4. Microbiology
5. Imuno-
serology
6. Therapeutic
drug
monitoring
Samples
1. Blood / serum/
plasma
2. Urine
3. Faeces
4. Cerebrospinal
fluid
5. Transudate /
exudate
Examination in the Clinical
Laboratory
1. Metabolyte
2. Enzym
3. Electrolyte
4. Proteine
5. Hormone
6. Antigen-
Bacteri/virus
7. Antibody
8. Allergen
9. Koagulation factors
10. ABO/Rhesus
11. HLA
12. Drugs
13. Trace elemen
Immuno-chemistry Methodes
 Generation 1 : RIA
(1980 early))
 Generation 2
(1980 medio : ELISA
EMIT
FPIA
Nephelometry
Generation 3 : IRMA
(1990) ELISA
Streptavidin-biotin
MEIA
CEDIA
ICMA

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