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    CRF

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    Gilank
    This document discusses chronic renal failure (CRF), which is a slow decrease in renal function over time that leads to an imbalance of water and electrolytes and increased waste buildup. CRF can be caused by conditions present from birth like kidney abnormalities or diseases that develop later in childhood such as genetic disorders or infections that cause inflammation of the kidneys. As CRF progresses, patients may experience fatigue, loss of appetite, and stunted growth, with end stage renal failure potentially resulting in uremia and coma if left untreated. Treatment aims to slow progression and replace kidney function through conservative management, dialysis, or transplantation.

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    CRF

    Uploaded by

    Gilank
    83 views7 pages
    This document discusses chronic renal failure (CRF), which is a slow decrease in renal function over time that leads to an imbalance of water and electrolytes and increased waste buildup. CRF can be caused by conditions present from birth like kidney abnormalities or diseases that develop later in childhood such as genetic disorders or infections that cause inflammation of the kidneys. As CRF progresses, patients may experience fatigue, loss of appetite, and stunted growth, with end stage renal failure potentially resulting in uremia and coma if left untreated. Treatment aims to slow progression and replace kidney function through conservative management, dialysis, or transplantation.

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    This document discusses chronic renal failure (CRF), which is a slow decrease in renal function over time that leads to an imbalance of water and electrolytes and increased waste buildup. CRF can be caused by conditions present from birth like kidney abnormalities or diseases that develop later in childhood such as genetic disorders or infections that cause inflammation of the kidneys. As CRF progresses, patients may experience fatigue, loss of appetite, and stunted growth, with end stage renal failure potentially resulting in uremia and coma if left untreated. Treatment aims to slow progression and replace kidney function through conservative management, dialysis, or transplantation.

    Copyright:

    © All Rights Reserved
    Download as PPT, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as ppt, pdf, or txt
    83 views7 pages

    CRF

    Uploaded by

    Gilank
    This document discusses chronic renal failure (CRF), which is a slow decrease in renal function over time that leads to an imbalance of water and electrolytes and increased waste buildup. CRF can be caused by conditions present from birth like kidney abnormalities or diseases that develop later in childhood such as genetic disorders or infections that cause inflammation of the kidneys. As CRF progresses, patients may experience fatigue, loss of appetite, and stunted growth, with end stage renal failure potentially resulting in uremia and coma if left untreated. Treatment aims to slow progression and replace kidney function through conservative management, dialysis, or transplantation.

    Copyright:

    © All Rights Reserved
    Download as PPT, PDF, TXT or read online from Scribd
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    Download as ppt, pdf, or txt
    of 7

    The kidney to the right depicts the loss of kidney

    tissue in chronic renal failure.


    CHRONIC RENAL FAILURE (CRF)

    Renal function progresses to


    decrease slowly
    Imbalance of water & electrolyte
    Increased of waste products
    (Blood ureum & creatinin)

    1
    ETIOLOGY:
    < 5 years old:
    • Hypoplasia / Dysplasia kidney
    • Congenital structure of urinary tract
    • Vesicoureteral reflux
    • Congenital Nephrotic Syndrome
    5 – 15 years old :
    • Hereditary diseases: Alport’s syndrome,
    sistinuri
    • Primary glomerulonephritis: Nephritic
    Syndrome
    • Secondary glomerulonephritis : SLE, SHS
    2
    CLINICAL MANIFESTATIONS:
    1. Diminished Renal Reserve
    • No clinical signs
    • Lab. Examinations: Leukocyturia, Haematuria
    2. Renal Insufficiency:
    • Non specific clinical signs: Malaise, fatigue, headache,
    poor appetite, abdominal pain
    3. Chronic Renal Failure:
    • Signs of ARF  Acute on CRF
    • Stunted growth
    • Pale skin
    • Bone pain
    4. End stage Renal Failure (ESRF):
    • Unconscious
    • Uremic coma (Blood Ureum & Creatinin increased very
    high)
    • Convulsion 3
    TREATMENT
    1. Conservative Treatment:
    The aims of this treatment:
    • Preparing the child & family for the treatment of
    CRF
    • Slowly progression to End Stage RF
    2. Replacement therapy:
    The aims is to replace the function of the unfunction
    kidney by:
    • Dialysis:
    • Peritoneal dialysis (PD)
    • Hemodialysis
    • Transplantation 4
    Any
    Question
    s?

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