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  • CLM & VLM

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    Mohammad Syaifuddin Fahmie
    218 views6 pages
    Hookworm causes an itchy rash on the skin through accidental skin penetration by its larvae. Using proteases, the larvae penetrate hair follicles, cracks, or intact skin, then shed their outer layer and begin migrating within days. However, the larvae cannot penetrate deeper than the skin as they lack the enzyme to break through the basement membrane into the dermis. Albendazole is the treatment. Toxocara infection comes from ingesting worm eggs from dogs or cats and can affect internal organs like the liver, lungs, eyes, heart and brain, potentially causing seizures, heart inflammation or even death in severe cases.

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    Hookworm causes an itchy rash on the skin through accidental skin penetration by its larvae. Using proteases, the larvae penetrate hair follicles, cracks, or intact skin, then shed their outer layer and begin migrating within days. However, the larvae cannot penetrate deeper than the skin as they lack the enzyme to break through the basement membrane into the dermis. Albendazole is the treatment. Toxocara infection comes from ingesting worm eggs from dogs or cats and can affect internal organs like the liver, lungs, eyes, heart and brain, potentially causing seizures, heart inflammation or even death in severe cases.

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    218 views6 pages

    CLM & VLM

    Uploaded by

    Mohammad Syaifuddin Fahmie
    Hookworm causes an itchy rash on the skin through accidental skin penetration by its larvae. Using proteases, the larvae penetrate hair follicles, cracks, or intact skin, then shed their outer layer and begin migrating within days. However, the larvae cannot penetrate deeper than the skin as they lack the enzyme to break through the basement membrane into the dermis. Albendazole is the treatment. Toxocara infection comes from ingesting worm eggs from dogs or cats and can affect internal organs like the liver, lungs, eyes, heart and brain, potentially causing seizures, heart inflammation or even death in severe cases.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pptx, pdf, or txt
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    CLM & VLM

    • Hookworm = Ancylostoma caninum, braziliense


    • Erythematous, serpiginous, pruritic, cutaneous
    eruption caused by accidental percutaneous
    penetration
    • Using their proteases, larvae penetrate through
    follicles, fissures, or intact skin of the new host. After
    penetrating the stratum corneum, the larvae shed their
    natural cuticle. Usually, they begin migration within a
    few days.
    • Larvae lack the collagenase needed to penetrate the
    basement membrane and invade the dermis
    • Albendazole is the treatment of choice
    • Toxocara species, the ascarid of dogs and cats
    • severe infection and can suffer from seizures,
    myocarditis, and encephalitis. Death has also
    been reported in some cases.
    • Ingesting embryonated eggs
    • Organ = Liver, lungs, eye, heart, and brain

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