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Urine Cytology
Urine Cytology
Urine Cytology
Edi Wibowo
1st reported by Papanicollaou and Marshall (1945)
Bladder Retrograde
washing or catheterization Direct Brushing
barbotage of ureters
Koss LG, Hoda RS. 2012. Chapter 2 Indication, Collection, and Laboratory Processing of Cytologic
Samples. Koss’s Cytology of the Urinary Tract with Histopathologic Correlations. Springer.7-
16.
Reporting Systems by G. Papanicolaou
• Class 1- Absence of abnormal or atypical cells
• Class 2- Atypical cells present but without abnormal
features
• Class 3- Cells with abnormal features but not
sufficiently pathognomonic
• Class 4- Fair number of pathognomonic cells and
cell clusters
• Class 5- Large number of conclusive cells and cell
clusters
Bhat A, Manjunath J, Manjunath S. Urine Cytology a Review. Annals of Applied Bio-Sciences .
2016.3(1):6-10.
• The positive predictive value was 94.8% for positive
cytology (Class 4 or 5)
• 47.4% for suspicious cytology (Class 3)
• 7.4% for negative cytology (Class 1 or 2)