A WIRELESS- IMPLANTABLE MICRO SYSTEM FOR

CONTINUES BLOOD GLUCOSE MONITORING

ANOOP P
Roll No:07
Reg. No:CTAHEEC013
 ABSTRACT

• Remotely powered implantable micro system

• Consists of a micro fabricated glucose biosensor
flip-chip bonded to a transponder chip
• Transponder chip measures the output signal of
the glucose biosensor and transmits to the
external reader
• Chip can measure the sensor output current
ranging from 1 nA to 1 A
 LITERATURE SURVEY

1. NON-CONTINOUS BLOOD GLUCOSE MONITORING 

• Consist of a blood glucose meters
• small drop of blood is needed to place on
test strip
 LITERATURE SURVEY

2. Continues wired blood glucose monitoring

• Used conventional electrochemical glucose
sensors
• Large sizes
• Wired
DESIGN
 DESIGN

• Microfabricating the glucose sensor

• Inegrating all the interfacing circuits into a
integral chip(TRANSPONDER CHIP)
• Attaching the microfabricated glucose sensor
to the transponder chip using flip chip
bonding
SYSTEM OVERVIEW AND FUNCTIONING
 SYSTEM OVERVIEW AND FUNCTIONING

• Monitoring system consisting of an

implantable microsystem and an external
reader.
• Microsystem measures the blood glucose
concentration and transmits the measured
data to the external reader
 GLUCOSE SENSOR

• Amperometric electrochemical biosensor

• Consists of three electrodes:
1)a working electrode(WE)
2)a reference electrode(RE)
3)a counter electrode(CE)
 ELECTRODES

1. WORKING ELECTRODE
• Act as a surface on which the electrochemical
reaction takes place between the glucose and
an enzymatic layer
• It catalyzes the oxidation of glucose to
gluconic acid
 ELECTRODES

2. REFERENCE ELECTRODE
• The reference electrode is used to measure the
solution (blood or interstitial fluid) potential
 ELECTRODES

3. COUNTER ELECTRODE
• An inert conductor (gold) that supplies the current
required for the electrochemical reaction
 TRANSPONDER CHIP

1. RF FRONT-END BLOCK
 TRANSPONDER CHIP

2. DATA-ACQUISITION
EXTERNAL READER
 ADVANTAGES

• Small size of the implant

• No need of oxygen
• Use of passive telemetry link
 CONCLUSION
• Miniaturization procedure for a wireless-
implantable microsystem for continuous blood
glucose monitoring
• Low cost procedure
• Microsystem implanted just underneath the
skin
 REFERENCES

• IEEE Trans.Biomed. Eng., vol. 35, no. 7, pp. 526–532,

Jul. 1988.
• IEEE Trans. Biomed.Eng., vol. 41, no. 10, pp. 937–942,
Oct. 1994.
• Biosensors Bioelectron., vol. 10, pp. 485–494, 1995
THANK YOU