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DASAR EPIDEMIOLOGI

Study Design - Cohort


Ikes Dwiastuti, S.KM.,M.Epid

Tes SKB CPNS 2018 – Dosen Asisten Ahli – Microteaching – 13-15 Desember 2018
Description
Mata Kuliah : Dasar Epidemiologi
Semester : II
Session : XI
Kompetensi Utama : 1. Kemampuan mengkaji dan menganalisis situasi kesehatan
masyarakat
2. Menguasai dasar ilmu kesehatan masyarakat
Kompetensi Pendukung : 1. Mampu melakukan penelitian masalah kesehatan yang
terdapat dalam masyarakat
2. Mampu menelaah artikel ilmiah bidang epidemiologi

Learning Outcome : 1. Mampu melakukan kajian dan analisis situasi


2. Memiliki penguasaan ilmu kesehatan masyarakat
Review
Typology of Epidemiology Study

Observational Study Designs Experimental Study Designs

Person level Aggregate level Clinical Trials


unit unit

Cross Sectional
Ecological
Studies Field Trials
Studies

Longitudinal
Studies Community Trials

Case Control
Studies Cohort Studies
Definition
Cohort Study:
= Follow-up, incidence, panel or prospective study

Involves a design in which information about the


study factor (exposure and non exposure) is known
for all subjects at the beginning of the follow up
period
Objective of cohort study
to compare:

an incidence rate in an exposed population to the rate


that would have been observed in the
same population, at the same time
if it had not been exposed
Design of Cohort Study
Begin with:
Defined Population

Non randomized

Identify: Exposed Not Exposed

Follow:

Do not Do not
Develop Develop
Develop Develop
disease disease
disease disease
Design of Cohort Study
Design of Cohort Study
Types of Cohort Study

 Prospective Study :
looks forward, looks to the future, examines future
events, follows a condition, concern or disease into
the future
 Retrospective Study
“to look back”, looks back in time to study events
that have already occurred
Types of Cohort Study
Prospective Study :

2018
Types of Cohort Study
Prospective Study :

2018
Types of Cohort Study
Retrospective Study : 2008

2018
Result of Cohort Study
 Rate & Risk (measures of frequency)
 Rate/Risk difference (measures of impact)
 Rate Ratio (strength of association)
Effect measures in cohort studies
 Absolute measures
- Risk Difference (RD) : Ie – Iue

 Relative measures
Ie
- Relative Risk (RR) :
Iue

Ie = incidence in exposed
Iue= incidence in unexposed
Effect measures in cohort studies
 Absolute measures
- Risk Difference (RD) : Ie – Iue
: 0,028 – 0,0174 = 0,0106
 Relative measures
I
- Relative Risk (RR) : e
Iue

0,028
: = 1,61
0,0174
Ie = incidence in exposed
Iue= incidence in unexposed
References
 Gordis, Leon, 2009, Epidemiology, Fourth Edition, Philadelphia: Saunders Elsevier.
 Gerstman, B.Burt, 2003, Epidemiology Kept Simple: An Introduction to Traditional
& Modern Epidemiology, 2nd edition, New Jersey : a John Wiley & Sons, Inc.,
Publication
THANK YOU ...

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