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Sex Chromatin Bodies: Barr Body
Sex Chromatin Bodies: Barr Body
Barr body
Organism No. chromosomes
Human 46
Chimpanzee 48
Dog 78
Horse 64
Chicken 78
Goldfish 94
Fruit fly 8
Mosquito 6
Nematode 11(m), 12(f)
Horsetail 216
Sequoia 22
Round worm 2
What Exactly is a chromosome?
Chromosomes are the rod-shaped,
filamentous bodies present in the nucleus,
which become visible during cell division.
OR
•Inactivate one of the X-chromosomes
in females.
Levels of enzymes or proteins encoded by
genes on the X chromosome are the same in
both males and females
XO individuals are
female but have no
Barr bodies.
46, XX 1 Barr body
45, X 0 Barr body
47, XXY 1 Barr body
47, XXX 2 Barr bodies
48, XXXX 3 Barr bodies
This gene codes for an enzyme that breaks down sugar which
helps red blood cells work properly.
22.3
pseudoautosomal region
22.2 region that escapes X-
22.1 inactivation
21.3
Duchenne Muscular
21.2
11.3 pseudoautosomal region
p 21.1
11.4
11.3
Dystrophy locus
p 11.2 SRY (testes determining
11.23 11.1 factor)
11.22 11.21
11.21 11.221
11.1 11.222
11.2 11.223
12
AZF (azoospermia factor)
13
X-inactivation center, XIST q 11.23
(sperm development)
12
21.1 heterochromatin
21.2
21.3
22.1 critical region for
q 22.2
22.3
23 ovarian development
24
25
26
27
Fragile X (FMR-1) locus
28
pseudoautosomal region
Presence of Barr bodies in a buccal smear was introduced by
the International Olympic Committee Medical Commission as a
sex determination (gender verification) test in 1968.
This test, known as the Barr test or buccal smear sex test, was
responsible for excluding about one female competitor in 400
from international competition. Six female competitors failed the
test in the 1984 Los Angeles Olympic games.
Soundarajan won a silver medal in the women's800 m race at the 2006 Asian Games held in Doha ,
Qatar ]However, she underwent a sex test shortly afterwards, and the results indicated that she "does
not possess the sexual characteristics of a woman .Soon after the results of the sex test came out,
she was stripped of her silver medal [.
In September 2007, Soundarajan
was reported to have attempted
suicide