Designing and Fabricating a T mixer, serpentine

mixer and Y mixer using Soft lithography..

-Aakash Goel (2015ABPS0771H)

-Pritish Dey Sarkar (2015A2A40618H)
-Shagun Srivastava (2015B1A10699H)
-Arush Tayal (2015A1PS0718H)
 Relevance to Microfluidics
• No energy input, but pressure head is being used to drive the flow of fluid.

• The Reynold’s number in a microchannel is very small (of the order

of 0.1).

• Parameters of concern are:

i) Re = (Velocity)(Hydraulic diameter)/(Kinematic viscosity)
ii) Pe = (Velocity)(Length of mixing path)/(Diffusion coefficient)

• Methods to generate chaotic advection (improving mixing index):

(a) Providing different holes for input of fluids.
(b) Providing with as many turns as possible along the channel.
(c) Introducing concept of splitting and recombination.
 Plan Of Work

Master Fabrication of
PDMS Mold Measurements
Preparation Replica
from the and
Through 3-D Molding
master. Calculations
Printing
 Parameters

• T-mixer: Two inlets of width 100 micron each, outlet

diameter is 200 micron.
• Y mixer: Two inlets of width 100 micron each,
intermediate angle of ---60o, outlet diameter is 200
micron
• Serpentine mixer: Channel width: 450 micron,
depth: 260 micron, wall width: 150 micron
• Mixing index:

C (outlet concentration gradient) can be measured

using colorimetry or spectrophotometry.
 References
1. S.H. Wong, M.C.L. Ward, C.W. Wharton, Micro T-mixer as a rapid mixing
micromixer, Sensors and Actuators B 100 (2004) 359–379.
2. Y. Xia, G.M. Whitesides, Soft Lithography, Angew. Chem. Int. Ed. 1998, 37, 550
– 575.
3. Shou-Shing Hsieh, Jyun-Wei Lin, Jyun-Hong Chen, Mixing efficiency of Y-type
micromixers with different angles, International Journal of Heat and Fluid Flow
44 (2013) 130–139
4. Jaehyun Park, Heesung Park, Thermal cycling characteristics of a 3D-printed
serpentine microchannel for DNA amplification by polymerase chain reaction,
Sensors and Actuators: A Physical https://doi.org/10.1016/j.sna.2017.10.044
5. Effective mixing in a short serpentine split-and-recombination micromixer,
Wasim Raza, Shakhawat Hossain, Kwang-Yong Kim, Sensors and Actuators B:
Chemical, Volume 258, 1 April 2018, Pages 381-392
6. Passive mixers in microfluidic systems: A review, Chia-Yen Lee, Wen-Teng
Wang, Chan-Chiung Liu, Lung-Ming Fu, Chemical Engineering Journal, Volume
288, 15 March 2016, Pages 146-160