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Experiment 3 - Frog Nerve
Experiment 3 - Frog Nerve
The smallest voltage required to produce the maximum CAP was 400 mV. In
order to produce maximal response, all nerves must be excited.
4.In this exercise, you examined the effect of increasing stimulus intensity on the
nerve. What other stimulus parameter might also affect the nerve's tendency to
generate a CAP?
Other stimulus parameter that might affect the nerve’s tendency to generate
a CAP is the stimulus frequency.
5.Explain the difference between the relative and absolute refractory periods.
- The cellular event responsible for the refractory period is the build-up of
potassium during repolarization because during its transition to
hyperpolarization, the build-up of potassium makes it more difficult for the
stimulus to reach the threshold.
7.Based on your calculation for CAP conduction velocity, how long would it take the
CAP to travel the length of the sciatic nerve? Assume a total length of 10 cm.
- Based on our calculation for CAP conduction velocity, it would take 0.0013
seconds for the CAP to travel 10 centimeters of sciatic nerve.
References:
Brink Jr, F. Linear range of Na+ pump in
sciatic nerve of frog. AJP – Cell
Physiology. 1983; Vol 244, Issue 3 198-C204
Effects of nerve impulses on threshold of frog sciatic nerve fibres. (n.d.). doi:10.3897/bdj.4.e7720.figure2f