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The Natural History of Degenerative Spondylolisthesis of

the Cervical Spine With 2-to 7-Year Follow-up
Moon Soo Park, MD, PhD,* Seong-Hwan Moon, MD,† Hwan-Mo Lee, MD,†
Seok Woo Kim, MD,* Tae-Hwan Kim, MD,* Bo-Kyung Suh, MD,*and K.
Daniel Riew, MD§

Department of Orthopaedic Surgery, Hallym University Sacred Heart

Hospital, Medical College of Hallym University, 896, Pyeongchon-dong,
Dongan-gu, Anyang-si, Gyeonggi-do, 431-070, Republic of Korea
†Department of Orthopaedic Surgery, Yonsei University College of Medicine,
250 Seongsan-ro, Seodaemun-gu, Seoul 102-752 , Republic of Korea

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• Cervical degenerative spondylolisthesis is common in patients older than

50, who sometimes require surgical treatment due to clinical symptoms.
• There is no report regarding its natural history.
• We report a retrospective case series of 27 patients with cervical
degenerative spondylolisthesis assessed by neutral and dynamic lateral
radiographs of the cervical spine with a mean follow up period of 39.0
months (range, 24-92).
• None of the anterolistheses or retrolistheses had progressed by the final
visit.

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 In conclusion, our results suggest that cervical degenerative

anterolisthesis and retrolisthesis appear to be stable over 2 to nearly 8
years.
 While those with retrolisthesis appear to have a higher propensity to
increase their subluxation, none dislocated or suffered neurologic
damage.
 In the absence of neurologic symptoms, we recommend observation of
patients with degenerative spondylolistheses of the cervical spine

Copyright © 2012 Lippincott Williams & Wilkins. Unauthorized commercial reproduction of this slide is prohibited