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Perkin Reaction
Perkin Reaction
PREM
2015A5PS862H
Introduction
The Perkin reaction is an organic reaction used to convert an aromatic
aldehyde and an anhydride to an α,β-unsaturated carboxylic acid
It is aldol condensation of an aromatic aldehyde and an acid anhydride
(which contain alpha hydrogen), in the presence of an alkali salt of the
acid.
The alkali salt acts as a base catalyst, and other bases can be used
instead.
as sodium acetate or potassium carbonate
The regiochemistry of the reaction, the relative position of the
carboxylic acid and aromatic ring in the final product, can be either E
or Z