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Anatomy of Duodenum
Anatomy of Duodenum
Anatomy of Duodenum
Source :sabiston textbook of surgery : the biological basis of modern surgical practice, 20th edition
Motility
• Peristalsis consists of intestinal contractions
passing aborally at a rate of 1 to 2 cm/sec.
• Pacesetter potentials, which are thought to
originate in the duodenum, initiate a series of
contractions in the fed state that propel food
through the smallbowel.
Source :sabiston textbook of surgery : the biological basis of modern surgical practice, 20th edition
Histology
• consists of four layers:
– the mucosa with the lining epithelium, lamina propria ,
muscularis mucosae;
– the underlying connective tissue submucosa with the
mucous duodenal (Brunner’s) glands;
– the two smooth muscle layers of the muscularis externa;
– the visceral peritoneum serosa (15).
• Villi in duodenum are broad, tall, and numerous, with
fewer goblet cells in the epothelium.
• Branched duodenal (Brunner’s) glands with mucus-
secreting cells in the submucosa characterize this
region
Source :diFiore’s, Atlas of Histology with Functional Correlations eleventh Edition
Source :diFiore’s, Atlas of Histology with Functional Correlations eleventh Edition
Functional Correlations
• Duodenal glands secrete or release their
product into the lumen in response to the
entrance of acidic chyme from the stomach
and parasympathetic stimulation by the vagus
nerve.
• The main function of the duodenal glands is to
protect the mucosa from the highly corrosive
action of the gastric contents.
Source :diFiore’s, Atlas of Histology with Functional Correlations eleventh Edition