Spiral Photonic Crystal Fiber-Based

Dual-Polarized
Surface Plasmon Resonance
Biosensor
What is Biosensor ?

A Biosensor is an analytical device. The sensor which

integrates the biological elements with the Physiochemical
transducer to produce an electronic signal is proportional
to a single analyte and which is fetched into a detector.
Optical Biosensor

 The Optical biosensor is a device that uses an optical measurement

principle. They use the fiber optics as well as optoelectronic
transducers. The term optrode represents a compression of the two
terms optical & electrode. These sensors mainly involve antibodies
and enzymes like the transducing elements.
What is Surface plasmon resonance
& how it works ?
 Surface Plasmon Resonance is a phenomenon that occurs when
polarized light hits a metal film at the interface of media with
different refractive indices.

 A light is incident upon a metal film through

 a prism and the reflected beam is collected

and analyzed.
What is Surface plasmon resonance
& how it works ?
 At a certain incident angle (or resonance angle), the plasmons are
set to resonate with light, resulting in absorption of light at that
angle. This creates a dark line in the reflected beam .

 The excitation of surface plasmons results in a dark line in the reflected beam, and
the angular position of the dark line shifts as a molecule binding event takes place.
What is Surface plasmon resonance
& how it works ?
 The resonance angle can be obtained by observing a dip in SPR
reflection intensity. A shift in the reflectivity curve represents a
molecular binding event taking place on or near the metal film.

 SPR Scanning Angle Response. SPR

 causes an intensity dip in the reflected
 light at the sensor surface. A shift in the
 curve represents molecular binding.
What is Surface plasmon resonance
& how it works ?
 By monitoring this shift vs. time we can study molecular binding
events and binding kinetics.

he angular shift vs. time provides a good study of

binding kinetics. The reverse process, molecular
dissociation, can be studied in a similar way.