RESEARCH PROPOSAL

INCIDENCE OF ZIKA VIRUS

OUTBREAK IN INDIA

BY
GROUP
ROLL NO: 157-174
 BACKGROUND OF THE STUDY
 On 15 May 2017, the ministry of Health and Family
Welfare-Government of India (MoHFW) reported
three laboratory-confirmed cases of Zika virus
disease in Bapunagar area, Ahmedabad District.
Gujarat, State, India.
 This report is important as it describes the first cases
of Zika virus infections and provides evidence on the
circulation of the virus in India.
 Therefore we took interest to research on this topic to
create awareness among Indian population.
 PROBLEM STATEMENT
characterizing Zika virus infection including
investigating public health and clinical
implications
developing and enhancing laboratory platforms
to support surveillance
piloting new vector control tools
 RESEARCH STATEMENT
To prevent an outbreak of Zika virus disease
and containment of spread in case of any
outbreak.
To create awareness on protection from
mosquitos bites among the high risk
population especially pregnant women.
To improvise sexual health education.
 SIGNIFICANCE OF THE STUDY
 Improve counseling of patients about risks during
pregnancy
 Inform best practices for the care of pregnant women with
Zika virus infection and their infants
 Identify and refer children for services they need as early
as possible
 Help agencies prepare to provide services to affected
children and families
 Inform policies to allocate resources and services to help
affected children and their families
 Improve prevention of Zika virus infection during
pregnancy
 LIMITATIONS OF THE STUDY
 Zika Virus, Dengue Virus, West Nile Virus and Chikungunya virus
have similar signs and symptoms.
 There is no certainty of Zika virus (ZIKV) cases due to lack of
serologic test
 Only rtPCR can diagnose ZIKV—that is, only on the first day of
acute infection (still, cross reactions can give a false positive)
 rtPCR cannot diagnose infection in infants, infants are diagnosed
clinically- microcephaly
 80% of ZIKV cases are unsymptomatic or oligosymptomatic
 The area being studied is endemic to the mosquito (A aegypti), which
is a vector for DENV, CHIKV, West Nile Virus, and ZIKV
 Coinfection of these viruses is not uncommon
 RESEARCH DESIGN
 Descriptive case study by using Routine laboratory survillence
through rt-PCR

DURING ANTENATAL CLINIC,

 Total 111 blood samples
 @ BJ medical college ahmedabad gujarat.
 sample from 22years old pregnant female has been tested positive

DURING ACUTE FEBRILE ILLNESS

 Total 93 blood samples survillence
 @BJ medical college ahmedabad gujarat.
 one sample from 64 year old male was found to be positive.