Hepatitis virus

Pre test and Post-test

 IgM anti-HAV IgG anti-HAV HBsAg Total Antibody HBeAg IgM anti- Anti-HBsAg
anti-HBcAg HBcAg

1 + - - - - - -

2 - - + + + + -

3 - - - + - - +

4 - - - - - - +
5. What hepatitis B gene will activate signal-transduction pathway that
eventually hyper-activate the viral enzymes leading to malignant damage to the
liver?
a) HBeAg
b) HBxAg
c) HBzAg
d) HBsAg
e) HBcAg
6. Hepatitis B infection requires antiviral therapy for full recovery and to
alleviate further damages toward liver’s hepatocytes, several drugs like Entecavir
and Lamivudine are used as 1st and 2nd line treatment for HBV infection
respectively, what are their mechanisms of action?
a) NRTI
b) NNRTI
c) Protease inhibitor
d) The same mechanism as delavirdine
e) The same mechanism as saquinavir
 7. The type of vaccine available to be used
against HBV infection is the same type as polio
oral vaccine
T/F?
8. What is the name of the core of a HDV?
a) Dane particle
b) Chromatic antigen
c) Delta antigen
d) Provirus particle
9. What serological result indicate an immune protective state against HBV
infection? (all answers are Antibody anti-…)
a) HBeAg
b) HBxAg
c) HBzAg
d) HBsAg
e) HBcAg
10. What is the gold standard for diagnosing people with HCV infection?
a) Rapid hepatitis antigen detection kit
b) RT-PCR
c) Biliary duct tissue biopsy
d) HIA
e) There is no definite standard, only clinical manifestations that serve as
evidence of infection.
 No serology
1. What is the function of HDV’s ribozyme?
2. What is the genome of HBV?
3. What virus is the most likely capable of causing a fulminant hepatitis out
of several hepatitis viruses explained before?
4. What is the other name of a complete HBV virion ?
5. What is the name of the core of a HDV?
6. From the following which one is/are considered as non-hematoinvasive
hepatitis virus?
1) HAV
2) HGV
3) HEV
4) HDV
7. What is the primary receptor for HBV infection?
8. What is the primary treatment for HEV?
9. What makes pararetroviridae to be different from retroviridae? Mention 2.
10. What is the vaccine type used to prevent infection against a patient with :
IgG-anti HAV (+) antibody anti-HBeAg (+) antibody anti-HBsAg (+)