Deep Vein Trombosis : Achievement of Treatment with Doppler Ultrasound

After 3 Months of Anticoagulant Therapy

M.Rizal Abdul Munaf, Andri Mardia, Henny Lubis, Dairion Gatot,

Hematology & Oncology Division, Internal Medicine Department, Medical Faculty, Universitas Sumatera Utara, General
Hospital Haji Adam Malik Medan

Introduction
Deep Vein Thrombosis is a manifestation of venous thromboembolism with complications such as pulmonary embolism and sudden death.
Anticoagulant therapy is usually used to consider and treat patients with deep vein thrombosis and recommended treatment for a minimum of 3 months
to 1 year

Method

Design : Observasional study

Location : RSUP H Adam Malik Medan
Time : February 1st 2018 to February 1st 2019

Inclusion Exclusion
Age> 18 years no result of initial doppler ultrasound
Diagonsa DVT from MR
Result
Data from MR Doppler
dan SIRS were USG Doppler (+) Giving anti- ultrasound
coagulant for 3 results 3
diagnosed DVT DVT months months after
Characteristics N=100 % 2018 therapy
Gender
Male 47 47
Female 53 53
Aged 56,78±10,99
17-25 3 3,0 USG Doppler After treatment N= 34 %
26-35 6 6,0
36-45 8 8,0 Bilateral 19 55,9
46-55 30 30,0
56-65 33 33,0 Unilateral 11 32,4
>65 20 20,0
DVT Category USG Doppler (-) DVT 4 11,8
Bilateral 63 63
Unilateral 37 37 Non- DVT DVT
Parameter Malignancy p Parameter p
Basic Illness Malignancy Bilateral Unilateral

Malignancy 37 37 1838 474 543,5 500,0

D-Dimer 0,018* D-Dimer 0,582*
Non-Malignancy 63 63 (255-5865)b (96-5900)b (138-5900) (96-5865)
D-Dimer 399,12±198,35a 397,5 373,5 (100-
Fibrinogen 0,903* 389,5 324,5
(104-900)b 900)b Fibrinogen 0,762*
Fibrinogen 500 (96-5804)b (100-900) (183-900)
bnon normal distribution, median (min-maks)
a normal distribution, mean±SD * significant p<0,005
b non normal distribution, median (min-max)

Conclusion

This study showed the achievement of deep venous thrombosis treatment at Adam Malik Hospital at 1 year was only
11.76% from the results of normal ultrasound doppler examination with oral anticoagulants for 3 months

Refference
Ermiş, H and Ermiş, N, Anticoagulant therapy for acute venous thromboembolism, Turk Kardiyol Dern Ars 2017;45(6):563-571
LYON, C. Rivaroxaban vs. Warfarin for Treatment of DVT and PE, 2017
Kearon, Clive and Akl Elie A, Duration of anticoagulant therapy for deep vein thrombosis and pulmonary embolism, Blood 2014 Mar 20;123(12):1794-801
Streiff, Michael B. Et All, Guidance for the treatment of deep vein thrombosis and pulmonary embolism, J Thromb Thrombolysis (2016) 41:32–67
Vedantham S et all, Guidance for the use of thrombolytic therapy for the treatment of venous thromboembolism, J Thromb Thrombolysis (2016) 41:68–80