Ralph Green Blood 2017 129:2603-2611: ©2017 by American Society of Hematology

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Intersections of B12 and folate metabolism, the methionine cycle, folate cycle, and DNA

synthesis showing the methyl folate “trap.” The key intersection of B12 and folate occurs at the
methionine synthase (MS) reaction in which the one-carbon methyl group o...

Ralph Green Blood 2017;129:2603-2611

©2017 by American Society of Hematology

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