SYOK PADA ANAK

Inotropik dan Obat Vasoaktif

Drug Effect(s) Dose Range Comment
Norepinephrine Strong 0,05-1,5 Produce short-term
vasoconstrictor µg/kg/min rise in blood pressure

Weak effect on Cause increase O2

strength of heart consumption,
contraction tendency for
dysrhythmias
Epinephrine Increase HR and 0,05-3,0 May decrease renal
strength of µg/kg/min perfusion
contractions
Potent Cause high O2
vasoconstriction consumption in heart
Dopamine Strengthens 5-15µg/kg/min Should be
contractions administrated in
(throughout dose central vein
range)
Increase renal blood Increase risk of
flow (low- dysrhythmia at high
intermediate dose) dose
 Inotropik dan Obat Vasoaktif
Drug Effect(s) Dose Range Comment
Dobutamine Increase strength of 1-20 µg/kg/min Very weak
heart contraction vasoconstriction
(high dose)
Less effect to heart Good cardiogenic
shock, strengthens
heart contractility
and produce
afterload reduction
Peripheral
vasodilator,
espcially in vessels
to viscera