Cavir 0.

5
 Entecavir 0.5 mg
(Guanosine nuclioside analog)
 Oral antiviral drug
 Cavir
 Chronic hepatitis B virus infection in adults with compensated liver
disease.
 Cavir
Indication
 Evidence of viral replication
 Evidence of persistent elevations in serum aminotransferases
(ALT or AST) or histologically active liver inflammation or
fibrosis.
 prevent cirrhosis or liver cancer.
Renal impairment
 In those with both HIV/AIDS and HBV antiretroviral
medication
 Cavir
MOA
 Prevents certain virus cells from multiplying in your body
 Entecavir is a guanosine nucleoside analogue with selective
activity against hepatitis B virus (HBV).
 Inhibit the Hepatitis B virus, blocking all three steps in the
replication process.
 Entecavir is more efficient than an older Hepatitis B drug,
lamivudine.
  Decrease the amount of hepatitis B virus in your body
Dosage & Administration
 Cavir should be administered on an empty stomach (at least 2

hours after a meal or 2 hours before the next meal).

 Nucleoside-treatment-naive (16 years): 0.5 mg once daily.
Lamivudine-refractory or known lamivudine or Telbivudine
resistance mutations (16 years): 1 mg once daily.
 Well tolerated with good safety profile
 Limited porential for resistace
 Silcox
 Salymarin and B Complex
 To support liver health

Salymarin
 Silcox
 Hepato-protective agent
 Support liver regeneration
 Enhancing immunomodulation
 Anti-fibrotic activity
 Anti-oxidant and Anti-neoplastic effect
 Anti-inflammatory
 Lowered high cholestrol
 Anti-demulcent
 Enhance detoxification process
 Silcox
Indication
 Cirrhosis
 Alcoholic liver disease
 Chronic hepatitis
 Fatty liver
 Diabetes
 Convalescence
 AVS – 10 mg
 Atorvastatin 10 mg tablets
 HMG Co-A reductase inhibitor (Statins)
 Lipid lowering agent
 lower "bad" cholesterol and fats (LDL,Triglyceride)
 raise "good" cholesterol (HDL) in the blood.
 AVS
Indication
 Family history of hyperlipidemia
 High Blood Pressure
 Age
 Low HDL
 Smoking
 Reduce the risk of stroke and heart attack and other heart
complications in people with type 2 diabetes, coronary heart
disease, or other risk factors.
Side effects
 constipation,diarrhea,nausea,fatigue,gas,heartburn,headache and
mild muscle pain.

Dose for Hyperlipidemia

 Initial dose: 10 mg or 20 mg orally once a day;
 an initial dose of 40 mg may be used in patients who require a
reduction in low density lipoprotein (LDL-C) of more than 45%
-Maintenance dose: 10 mg to 80 mg orally once a day
 RVS – 10 mg
 RVS a Perfect Choice

 Rosuvastatin Calcium 10 mg Tablets

 HMG Co-A reductase inhibitor(Statins)

 Lipid lowering agent

 lower "bad" cholesterol and fats (LDL,Triglyceride)

 raise "good" cholesterol (HDL) in the blood.

 RVS – 10 mg
 Treatment of high LDL Cholesterol (dyslipidemia)
 Hyperlipidemia
 Hypercholesterolemia
 Hypertriglyceridemia
 Atherosclerosis
 Decrease the relative risk of heart attack and stroke
 reduce cardiovascular risk by exerting anti-inflammatory effects on
vascular wall
 Hyperlipoproteinemia Type III (Elevated beta-VLDL + IDL)
 Homozygous Familial Hypercholesterolemia
 RVS – 10 mg
Dosage
 Take statins at bedtime because Cholesterol production in the
liver is highest after midnight and lowest during the morning
and early
 Initial dose: 10 mg to 20 mg orally once a day
Maintenance dose: 5 mg to 40 mg orally once a day afternoon
 LAXIWAL
 Each 15 ml contains

 Lactulose (as Lactulose concentrate U.S.P ) 10 ml

 Laxative solution
 LAXIWAL
 To treat or prevent complications of liver disease
(hepatic encephalopathy).
 Lactulose is a colonic acidifier that works by decreasing the
amount of ammonia in the blood. It is a man-made sugar
solution.
 Lactulose relieves constipation by drawing water into the bowel
to make poo softer.
 Unlike other laxatives that stimulate the bowels, the long-term
use of lactulose does not lead to dependency and addiction.
 LAXIWAL
Indication
Constipation
Portal Systemic Encephalopathy
Orlis
 Orlis
 Orlistat 120 mg Capsules U.S.P
 Lipase inhibitor
 Obesity management
 Weight lost
 Weight maintainance
 Orlis
MOA
 Irreversible inhibitor of gastric and pancreatic
Lipase decreases dietary fat absorption
 Inactivated enzyme inhibit dialysis of
dietary fat (TG) to absorable free fatty acid
and moniglycerides
 Dose dependent increase in faecal fat

excretion.
 Proven weight loss in over 15,000 patients
 Local mechanism of action with better safety profile
 Beneficial effect on hypertension and Dyslipdaemia
 45 % risk reduction in type 2 Diabetes
 Block some of the fat that you eat,keeping it from
being absorbed by your body
 BCAA
Branch Chain Amino Acids 1000mg
 L-Leucine 500mg
 L-Isoleucine 250mg
 L-Valine 250mg

BCAA
Induces muscle protein synthesis via S6K
 Promotes glucose uptake into muscle cells
 Stimulates insulin secretion from the pancreas

Indication
 To improve hypoalbuminemia in patients with decompensated liver
cirrhosis
 To promote gains in muscle in people ith lower dietary protein intake and
in the elderly
 To prevent fatigue in novice athletes
 BCAA
Dosage
 2 Tab daily
 4 Tab for HE patients (အသည)ရင)သ)
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 Calcibone-D
Calcium and vitamin D

 The two most important nutrients

 for bone health

Indication
Calcibone-D
 People who spend little time in the sun or those who regularly cover up when outdoors;
 People living in nursing homes or other institutions or who are homebound;
 People with certain medical conditions such as Celiac disease and inflammatory bowel
disease;
 People taking medicines that attect vitamin D levels such as certain antiseizure
medicines;
 People with very dark skin;
 Obese or very overweight people;
 Older adults with certain risk factors
 Actibile 150/300
 Ursodeoxycholic acid / Ursodiol

(150/300 mg)

 Primary bilary cirrosis

 Gallbladder stones
 Actibile 150/300
 Actively corrects the bile
 Dissolve certain types of gallstones
 Indication
 Primary biliary cirrhosis
 To treat small gallstones in people who cannot have gallbladder surgery
 To prevent gallstones in overweight patients undergoing rapid weight loss
 Dosage
 8-15mg/kg/day for 24 months
 Milk Thistle
 Protect the liver by displacing liver-binding toins, which
allows for faster healing, and by stabilizing the membranes of
liver cells, through its antioxidant capacities
 Inhabit the division of cancer cells and promoting early cancer
cell death
 Immunostimulatory effects
 Milk Thistle
Indication
 Alcoholic hepatitis
 Liver cirrhosis

Dosage
1-2 Tab daily
Cod Liver Oil 400/1000
 Vit A
 Vit D
 Omega-3 fatty acids: EPA & DHA
 Cod Liver Oil 400/1000
 Healthier blood vessels, lower lipid count, and reduced risk for plaque buildup
 Reduce the risk of CHD
 Support immune system
 Decrease the risk of diabetes & several forms of cancer including breast cancer
 Preserve brain health
 Maintain healthy mucous membranes of the respiratory & digestive tracts
 Maintains bone health
 Support healthy skin
 Improve the Symptos of rheumatoid arthritis
 OZG
 Omeprazole 20mg
 PPI
 Suppress gastric acid secretion
 Promote healing more rapidly than H2 blockers
 OZG
Indication
 GU or DU
 GERD
 Erosive oesophagitis
 Zollinger-Ellison syndrome
 Treatment & prevention of recurrence of NSAID associated GU
 Recurrence of DU associated with H.pylori infection
 Heartburn
 Nocturnal acid breakthrough
 OZG
Dosage
 20mg once daily for 4 weeks in DU, 8 weeks in GU
 40mg once daily for recurrent or severe cases