The body’s waterway that gives

route to the molecules to be

transported to the different
parts of the body is known as
______________________.
Fats, which we refer to as lipids,
are said to be water-fearing or
otherwise known as
_______________.
PROBLEM!!!

How can fats be transported to

the different parts of the body
where they are needed?
Thanks to . . .
What makes lipoprotein capable of
transporting fats (which are
hydrophobic) through the
bloodstream?
What is L I P O P R O T E I N ?

LIPID

+ = LIPOPROTEIN
PROTEIN
LIPOPROTEINS are . . .
complex aggregates ('particles') of lipids and
proteins that render the hydrophobic lipids
compatible with the aqueous environment of body
fluids and enable their transport throughout the
body of all vertebrates and insects to tissues where
they are required.

synthesized mainly in the intestines and liver.

 STRUCTURE
sphericial to discoidal in shape

core of non-polar lipids,

triacylglycerols and cholesterol
esters

surface monolayer, consisting

of apoproteins, phospholipids
and non-esterified cholesterol
 CLASSIFICATIONS
High-
Low- Density
Very Low-
Chylomicron Density Lipoprotein
Density
Lipoprotein (HDL)
Lipoprotein
(LDL)
(VLDL)

based on relative densities of the aggregates

C
H transports lipids
Y (triglycerides)
L
O mucosal
M cells in different
I the small body cells
C intestines
R
O
N
V transports lipids
(triglycerides & cholesterol)

L different
liver
D body cells

L High triglycerides in the blood

may increase the risk of coronary
artery disease
 last remnants of VLDL

L
(chiefly cholesterol)

D liver different
body cells

L
 last remnants of VLDL

L
(chiefly cholesterol)

D liver different
body cells

L High cholesterol on the arterial

wall is the primary responsible
for atherosclerosis.
 transports excess or
unused cholesterol
H
body’s
D tissues
liver

L “Good cholesterol!”
High HDL means lowered risk of
cardiovascular disease.
1. Choresterol is the most abundant steroid lipid in the body, it plays a
vital role in the cell repair and the formation of new cells. What will
happen if the cholesterol combines with other compounds in your
blood?
A. Your blood circulation will be stable and increase your heart rate.
B. It can build up as plaque in your arteries, blocking blood flow to and
from the heart and thus increases your risk of cardiovascular
disease.
C. Increase the risk of airborne disease.
D. It increases the risk of respiratory disease.
2. When certain lipids are placed into water, they spontaneously
rearrange themselves to form lipid aggregates. What specific lipid
when placed in an aqueous environment will spontaneously form a
structure called micelles?
A. Phospholipids
B. Glycolipids
C. Fatty Acids
D. Lipids
3. Lipid aggregates can be classify into three major membranes, the
micelle, bilayer and liposomes. Each aggregate have different
properties but they have similar “driving force” that led them to
form membranes. What is the driving force?
A. London forces
B. Hydrogen bonds
C. Hydrophobic effect
D. Electric and hydrogen bonds
4. The following are functions of lipids in the cellular processes, which
of the following is INCORRECT?

A. It facilitate cell to cell recognition

B. It Increases your blood sugar level
C. It regulates the entry of ions, solvents and molecules
D. It serves as energy storage for future use
5. What will be formed when a carbohydrates is attracted to
phospholipid?
A. Micelle
B. Steroid
C. Glycolipid
D. Phospholipid bilayer
6. A phospholipid is composed by a hydrophilic held and hydrophobic
tails. Hence, it is a ___________.

A. Amphipathic
B. Dynamic
C. polar
D. Non-polar
7. Which of the following BEST defines or describe lipoproteins?

A. Lipoproteins are synthesized in the liver and intestines

B. Lipoproteins are soluble complexes of proteins and lipids that
transport lipids in the circulation of all vertebrates and even insects
C. Lipoproteins are insoluble aggregates of lipids and proteins where
enzymes are needed to transfer them to be different parts of our
body
D. Lipoproteins are classified as chlymicrons, VLDL, LDL, and HDL.
8. LDL is consist of chiefly cholesterol which result to an increase of
cardiovascular disease, hence, HDLs, Play an important role in
lowering the risk of heart diseases. Which of the following is the
BEST possible situation for a low risk of heart disease?

A. Huge amount of LDL must be brought back to the intestine by the

HDL so that lesser amount of cholesterol is found in the
bloodstream.
B. There should be a very low level of LDL in our body which is
beneficial to our health.
C. A zero level of LDL is the most beneficial to our health since no more
cholesterol are clogged in our bloodstream.
D. A high level of HDL must be produced in our body so that our total
cholesterol level must only be equal to our LDL level, hence, a lower
risk of heart disease.
9. Membrane fluidity is influenced by the following, EXCEPT:

A. Heat
B. Fatty Acid Composition
C. Temperature
D. Sterol Content
10. What is the kind of active transport which engulfs particles into
vesicle via pseudopodia formation?

A. Endocytosis
B. Phagocytosis
C. Exocytosis
D. Potocytosis