Scribd Logo
Upload

Welcome to Scribd!

  • Immunoglobulin D & E (Ig D & Ige) : Group 6

    Uploaded by

    Jaycee Toledo
    12 views6 pages
    Immunoglobulin D and E are types of antibodies that play specialized roles in the immune system. IgE is found in trace amounts in blood plasma and is responsible for type I hypersensitivity reactions and anaphylaxis. It binds strongly to receptors on mast cells and basophils. IgD is found at very low levels in plasma but is present in large quantities on the surface of circulating B lymphocytes, where it may play a role in B cell activation. Both IgD and IgE have short half-lives.

    Original Description:

    Immunoglobulin IgD & IgE

    Original Title

    Immunoglobulin

    Copyright

    © © All Rights Reserved

    Available Formats

    PPTX, PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    Immunoglobulin D and E are types of antibodies that play specialized roles in the immune system. IgE is found in trace amounts in blood plasma and is responsible for type I hypersensitivity reactions and anaphylaxis. It binds strongly to receptors on mast cells and basophils. IgD is found at very low levels in plasma but is present in large quantities on the surface of circulating B lymphocytes, where it may play a role in B cell activation. Both IgD and IgE have short half-lives.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pptx, pdf, or txt
    12 views6 pages

    Immunoglobulin D & E (Ig D & Ige) : Group 6

    Uploaded by

    Jaycee Toledo
    Immunoglobulin D and E are types of antibodies that play specialized roles in the immune system. IgE is found in trace amounts in blood plasma and is responsible for type I hypersensitivity reactions and anaphylaxis. It binds strongly to receptors on mast cells and basophils. IgD is found at very low levels in plasma but is present in large quantities on the surface of circulating B lymphocytes, where it may play a role in B cell activation. Both IgD and IgE have short half-lives.

    Copyright:

    © All Rights Reserved
    Download as PPTX, PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pptx, pdf, or txt
    of 6

    Immunoglobulin D & E

    (Ig D & IgE)


    Group 6
    Immunoglobulin E
    Turgeon Stevens
    • Also known as (Epsilon Heavy • Type I immediate hypersensitivity
    Chain)
    • Monomers • H chains
    • Trace plasma protein • Basophils
    • Found in the blood plasma of • Eosinophils
    unparasitized individuals.
    • Shortest half life • Anaphylactic shock
    • Release histamine, heparin, • Heat labile
    anaphylaxis for allergic reactions
    • Responsible for an individual • Lung and skin
    immunity to invading parasites.
    • IgE molecule binds strongly to a • Mast cells
    receptor on mast cells and
    basophils together with antigen
    Immunoglobulin D
    Turgeon Stevens
    • Also known as (Delta Heavy • It is the second type of
    Chain) immunoglobulin to appear
    • Monomers • It only represents less than 0.001
    percent of total immunoglobulin.
    • IgD is found in very low • 2 to 3 days of half life
    concentration in plasma and also
    the surface of B lymphocytes
    • Less than 1% of the total • It is represent in large quantities
    ig(immunoglobulin) pool on the membrane of many
    circulating immunocompetent B
    lymphocyte.
    • Extremely susceptible to • 180,000 molecular weight
    proteolysis
    • Primary cell membrane • B cell activation
    • Does not cross the placenta
    Immunoglobulin E
    Immunoglobulin D
    Thank You!!

    You might also like